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Case Report
1 MD (General Medicine), Senior Resident, Department of Medical Oncology, Institute of Obstetrics and Gynaecology, Egmore, Tamil Nadu, India
2 MSc, Clinical Oncology, Junior Resident, Department of Medical Oncology, Institute of Obstetrics and Gynaecology, Egmore, Tamil Nadu, India
3 DM (Medical Oncology), Head of the Department, Department of Medical Oncology, Institute of Obstetrics and Gynaecology, Egmore, Tamil Nadu, India
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Gayathri R Nair
Senior Resident, Department of Medical Oncology, Institute of Obstetrics and Gynaecology, Egmore, Tamil Nadu,
India
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Article ID: 101421Z01GN2023
Introduction: Cervical cancer is the most common gynecologic malignancy in India, the most common histology being squamous cell carcinoma. Malignant mixed Müllerian tumor of the cervix, also referred to as carcinosarcoma of the cervix is an unusual entity. Hence, there is a dearth of literature on evaluation and management of such tumors, which is also reflected in the fact that there are no specific consensus guidelines on the same. We present the case of a 35-year-old woman who was diagnosed to have malignant mixed Müllerian tumor of the cervix.
Case Report: Carcinosarcoma cervix is a rare entity, with postmenopausal women being more commonly affected. This makes our case a very unique one, as our patient is a premenopausal, 35-year-old young woman who presented with abnormal uterine bleeding and was subsequently diagnosed to have carcinosarcoma of the cervix. The clinical presentation and management of the case have been discussed.
Conclusion: Malignant mixed Müllerian tumor is an aggressive and rare tumor which can affect the uterus, ovaries, or the cervix. A negative biopsy may not help to rule out the diagnosis of the same. Multimodality treatment including surgical intervention, chemotherapy with paclitaxel and carboplatin, and radiotherapy could benefit this subset of patients.
Keywords: Carcinosarcoma, Cervical cancer, Gynecologic malignancies, Malignant mixed Müllerian tumor
Gayathri R Nair - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
V Jennifer - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
KVS Latha - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Gayathri R Nair et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.