Case Report
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Treatment of Epstein–Barr virus induced hemophagocytic lymphohistiocytosis with anti-CD20 therapy: A two-year follow-up | ||||||
Bijit Kumar Kundu1, Deepak Rath2 | ||||||
1MD, Associate Professor, Rheumatology Clinic, Department of Medicine, PGIMER & Dr RML Hospital, New Delhi, India 2MD, Postdoctoral Trainee, Department of Rheumatology, IPGMER & SSKM Hospital, Kolkata, India | ||||||
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Kundu BK, Rath D. Treatment of Epstein–Barr virus induced hemophagocytic lymphohistiocytosis with anti-CD20 therapy: A two-year follow-up. Int J Case Rep Images 2018;9(1):25–32. |
ABSTRACT
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Introduction: Hemophagocytic lymphohistiocytosis (HLH) is well known to the rheumatologist as a devastating complication of a rheumatologic disease, being one of the few rheumatologic emergencies. Its treatment is usually started on the basis of presumption without waiting for confirmatory evidence. The diagnosis of HLH is usually missed when it appears in any of its many and varied chronic manifestation. It can be a great mimic with symptoms pertaining to any organ system of the human body. Once diagnosed it is imperative to find the trigger in order to prevent recurrences. Keywords: Epstein–Barr virus, Hemophagocytic lymphohistiocytosis, Panniculitis, Rituximab |
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Author Contributions
Bijit Kumar Kundu – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Deepak Rath – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
Guarantor of Submission
The corresponding author is the guarantor of submission. |
Source of Support
None |
Conflict of Interest
Authors declare no conflict of interest. |
Copyright
© 2018 Bijit Kumar Kundu et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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