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Case Report
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| Dabska tumor of the tongue: A clinicopathological study with confocal laser scanning microscopy | ||||||
| Gianfranco Favia1, Luisa Limongelli2, Angela Tempesta2, Eugenio Maiorano3 | ||||||
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1MD, DDS, Ph.D Path, Ph.D Surg, Professor, Department of Interdisciplinary Medicine, Odontostomatology, Aldo Moro University, Bari, Italy.
2DMD, Department of Interdisciplinary Medicine, Odontostomatology, Aldo Moro University, Bari, Italy. 3MD, MS, Professor, Department of Emergency and Organ Transplantation, Pathological Anathomy, Aldo Moro University, Bari, Italy. | ||||||
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| How to cite this article |
| Favia G, Limongelli L, Tempesta A, Maiorano E. Dabska tumor of the tongue: A clinicopathological study with confocal laser scanning microscopy. Int J Case Rep Images 2015;6(1):46–50. |
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Abstract
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Introduction:
Dabska tumor, or papillary intra-lymphatic angioendothelioma (PILA), first described in 1969 by Dabska, is a rare vascular low grade malignancy that usually affects the skin and subcutaneous tissues of infants.
Case Report: We report a case of PILA of the right tongue in a 65 years old male patient presenting as a white-bluish multinodular lesion, measuring 4x3 cm. After wide excision, histological examination was carried out with confocal laser scanning microscopy (CLSM). The histological features seen during optical examination were: thin-walled vascular spaces resembling a cavernous lymphangioma, and the formation of prominent intraluminal papillary tufts with hyaline cores lined by hobnail endothelial cells. The CLSM analysis highlighted muscle infiltration, and high fluorescence of intraluminal papillary core due to the presence of young thin collagen fibers devoid of cross-links. Thus, a final diagnosis of PILA was made. Conclusion: Confocal laser scanning microscopy analysis could surely facilitate the histological diagnosis, allowing the identification of some features of the tumor. | |
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Keywords:
Benign vascular tumor, Confocal laser scanning microscope (CLSM), Dabska tumor, Papillary intra-lymphatic angioendothelioma (PILA)
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Author Contributions
Gianfranco Favia – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Luisa Limongelli – Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Angela Tempesta – Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Eugenio Maiorano – Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Gianfranco Favia et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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