Case Report
 
A rare cause of quadriplegia: Bilateral medial medullary syndrome presenting with "heart appearance sign"
Suryanarayana Sharma P. M.1, Mahendra J. V.2, Rohan R. Mahale2, Acharya P. T.3, Madhusudhan B. K.1, Srinivasa R.4
1D. M. Neurology Resident.Department of Neurology, M. S. Ramaiah Medical College, Bangalore, Karnataka, India.
2D. M. Neurology, Assistant Professor. Department of Neurology, M. S. Ramaiah Medical College, Bangalore, Karnataka, India.
3D. M. Neurology, Sr. Professor, Department of Neurology, M. S. Ramaiah Medical College, Bangalore, Karnataka, India.
4D. M. Neurology, Sr. Professor & Head, Department of Neurology, M. S. Ramaiah Medical College, Bangalore, Karnataka, India.

doi:10.5348/ijcri-201557-CR-10518

Address correspondence to:
Dr. Srinivasa R
Sr. Professor & Head, Department of Neurology, M. S. Ramaiah Institute of Neurosciences
M.S.Ramaiah Memorial Hospital, New B.E.L Road
Bangalore-560054, Karnataka
India
Phone: +91- 9448040589
Fax: +91-80-22183276

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How to cite this article
Sharma SPM, Mahendra JV, Mahale RR, Acharya PT, Madhusudhan BK, Srinivasa R. A rare cause of quadriplegia: Bilateral medial medullary syndrome presenting with "heart appearance sign". Int J Case Rep Images 2015;6(6):338–342.


Abstract
Introduction: Bilateral medial medullary infarct (MMI) is a very rare form of cerebrovascular disease presenting with quadriplegia, tongue weakness and posterior column sensory deficit. Initial reports of bilateral MMI were on autopsy. Only 38 magnetic resonance imaging (MRI) proven cases of bilateral MMI have been published in English literature till March 2011.
Case Report: In the present case, patient presented with progressive quadriplegia of three days duration with respiratory involvement, MRI scan of brain revealed diffusion restriction in bilateral paramedian medulla appearing as characteristic heart appearance sign diagnostic of bilateral MMI.
Conclusion: High index of suspicion is required to make early diagnosis in this rare stroke subtype. Optimal respiratory management may significantly improve the clinical outcome.

Keywords: Bilateral medial medullary infarct (MMI), Quadriplegia, Heart appearance sign


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Author Contributions
Suryanarayana Sharma P. M. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Rohan R. Mahale – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Mahendra J. V. – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Madhusudhan B. K. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Acharya P. T. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Srinivasa R. – Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
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The corresponding author is the guarantor of submission.
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Authors declare no conflict of interest.
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© 2015 Suryanarayana Sharma et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.