Submit
   
Case Report
 
Osteogenesis imperfecta complicated with psychosis secondary to complex partial seizures
Roya Samadi1, Ali Akhoundpour Manteghi2, Mehri Baghban Haghighi3, Shervin Assari4
1Psychiatry and Behavioral Sciences Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2Department of Psychiatry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4Department of Psychiatry, University of Michigan School of Medicine, Social Determinant of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

doi:10.5348/ijcri-201556-CR-10517

Address correspondence to:
Ali Akhoundpour Manteghi
MD, Psychiatry and Behavioral Sciences Research Center
Ibn-e-Sina Hospital, Faculty of Medicine, Mashhad University of Medical Sciences
Mashhad
Iran
Phone: +985117124184
Fax: +985117112540

Access full text article on other devices

  Access PDF of article on other devices

[HTML Full Text]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]


How to cite this article
Samadi R, A. Manteghi A, B. Haghighi M, Assari S. Osteogenesis imperfecta complicated with psychosis secondary to complex partial seizures. Int J Case Rep Images 2015;6(6):332–337.


Abstract
Introduction: Osteogenesis imperfecta (OI) is an uncommon hereditary connective tissue disorder affecting collagen type I. The most common manifestations are frequent bone fractures and deformities, blue sclera, dental abnormalities and hearing loss. Seizures and mental retardation are not so common.
Case Report: A 25-year-old male with usual symptoms of OI, mild mental retardation and a psychotic feature due to complex partial seizures, after an experience of head trauma. He was treated with risperidone, aripiprazole, oxcarbamazepine, alendronate and vitamin D3.
Conclusion: It seems that seizure in OI is more common than general population. This may happen probably as a result of the complications of the head trauma in background of osteogenesis imperfecta. Moreover, clinical manifestations of complex partial seizure, can be mistaken with primary psychosis. Mental retardation and hearing loss might complicate this manifestation. So, psychiatric counseling and neurological evaluations should be carried out in OI patients.

Keywords: Complex partial seizures, Lobstein syndrome, Osteogenesis imperfect, Psychosis


[HTML Full Text]   [PDF Full Text]
Author Contributions
Roya Samadi – Substantial contributions to conception and design, Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Ali Akhoundpour Manteghi – Substantial contributions to conception and design, Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mehri Baghban Haghighi – Acquisition of data, Drafting the article, Final approval of the version to be published
Shervin Assari – Acquisition of data, Drafting the article, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Roya Samadi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



About The Authors

Roya Samadi is psychiatrist at psychiatry and behavioral research center, Mashhad University of Medical Sciences, Mashhad, Iran. She graduated as a general physician from Azad Medical University, Mashhad, Iran. She then completed a psychiatry residency at Mashhad University of Medical Sciences, Mashhad, Iran. She has published 10 research papers in national and international peer review journals. Her research interests include psychosomatic disorders, psychopharmacology, and addiction.



Ali Akhoundpour Manteghi is Associate Professor at Psychiatry Department, Faculty of medicine, Mashad University of Medical Science, Mashad, Iran. He earned General Physician from Faculty of Medicine, Mashad University of Medical Science, Mashad, Iran and Psychiatry speciality from Mashhad University of Medical Sciences, Mashhad, Iran. He have published 15 research papers in national and international academic journals and authored 1 book. His research interests include Schizophrenia and PTSD.



Mehri Baghban-Haghighi is General Practitioner at Mashhad University of Medical Sciences, Mashhad, Iran. She earned the undergraduate degree general Medical Doctor from Mashhad University of Medical Sciences, Mashhad, Iran. She has published 12 research papers in national and international academic journals. Her research interests include psychiatry, psychosomatic medicine and neuropsychiatry. She intends to pursue psychiatry residency in future.



Shervin Assari is a faculty member at Department of Psychiatry, University of Michigan, Ann Arbor. He is trained as MD/MPH, with postdoctoral research training in health disparity. Assari has published 160 peer review manuscripts from which more than 100 appearin Pubmed. He is the Associate Editor of Frontiers in Psychiatry and Frontiers in Public Health, and peer reviewer for more than 40 journals. Assari studies the contextual effects of race, ethnicity,and gender on social, behavioral, and medical correlates of mood disorders. He has worked on a wide range of psychosocial outcomes suchas health care utilization, drug use, sexual behaviors, suicide, and chronic medical conditions.