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Case Report
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| Cutaneous sarcoidosis presenting with diffuse panniculitis: A case report | ||||||
| Assane Diop1, Diallo Moussa2, Maodo Ndiaye2, Abbaspour Valiollah2, Pauline Dioussé2, Boubacar Diatta2, Fatimata Ly1, Suzanne Oumou Niang2, Mame Thierno Dieng2, Assane Kane2 | ||||||
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1MD, Assistant Professor, Department of Dermatology, Institutd'HygiéneSociale, Faculty of Medicine, Cheikh Anta Diop University, Dakar, Senegal.
2MD, Assistant Professor, Department of Dermatology Hôpital Aristide le Dantec, Faculty of Medicine, Cheikh Anta Diop University, Dakar, Senegal. | ||||||
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| Diop A, Moussa D, Ndiaye M, Valiollah A, Dioussé P, Diatta B, Ly F, Niang SO, Dieng MT, Kane A. Cutaneous sarcoidosis presenting with diffuse panniculitis: A case report. Int J Case Rep Images 2015;6(6):328–331. |
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Abstract
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Introduction:
Cutaneous lesions in sarcoidosis are polymorphic. They can simulate most dermatological conditions. We report a case of cutaneous sarcoidosis presented as diffuse Panniculitis
Case Report: A 62-year-old male with no significant past medical history consulted for infiltrated lesion on abdominal skin infiltration lasting for two years. On examination, there were multiple indurated plaques, topped with keratotic papules giving an orange peel view, extending on abdominal genitalia and thighs skin associated with lymph nodes enlargement in different sizes and elastic consistence in axillary and inguinal regions. The histopathological examination of the skin lesion and the lymph nodes revealed typical sarcoidosis granulomas. Thoracic abdominal CT scan was normal. After six months of treatment with methotrexate and prednisone, evolution was remarkable by a rapidly skin lesions des infiltration and disappearance of lymphadenopathy. Conclusion: Cutaneous sarcoidosis as disseminated panniculitis is rarely reported in literature. In our patient, methotrexate combined with prednisone was effective. Other studies have confirmed the efficacy of methotrexate, especially as a steroid sparing treatment. This efficiency would be the result of adenosine production and a decrease in TNF a secretion in granulomatous lesions. | |
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Keywords:
Diffuse panniculitis, Methotrexate erythematous, Panniculitis, Sarcoidosis
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Author Contributions
Assane Diop – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Diallo Moussa – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Maodo Ndiaye – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Abbaspour Valiollah – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Pauline Dioussé – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Boubacar Diatta – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Fatimata Ly – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Suzanne Oumou Niang – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Mame Thierno Dieng – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Assane Kane – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Assane Diop et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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