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Case Report
1 St. Joseph’s Healthcare Hamilton Charlton Campus, Hamilton, Ontario, Canada
2 Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
3 McMaster Institute of Urology, Department of Surgery, McMaster University, Hamilton, Ontario, Canada
Address correspondence to:
Moaz Alowami
St. Joseph’s Healthcare Hamilton Charlton Campus, Hamilton, Ontario,
Canada
Message to Corresponding Author
Article ID: 101528Z01MA2026
Introduction: Bladder endocervicosis (BE) is a rare benign condition characterized by the presence of endocervical-type glands within the bladder wall. Prior Cesarean section or pelvic surgery appears to be a significant risk factor predisposing to BE. Chronic pelvic pain in women is a common symptom of BE. Bladder endocervicosis’s inherent capability to mimic malignancy radiologically and endoscopically may pose a clinical conundrum.
Case Report: A 38-year-old female presented with a five-year history of sharp, stabbing pelvic pain during urination. Magnetic resonance imaging (MRI) revealed a thickened bladder wall and abdominal scar tissue forming a connection between the lower uterine segment and the posterior dome of the urinary bladder. However, no identifiable mass was reported on MRI. Flexible cystoscopy revealed a solid, mass-like lesion with papillary projections on the posterior bladder wall. Histopathological examination of the urinary bladder mass-like lesion revealed benign urothelium with numerous scattered, irregular, and dilated glands lined by columnar mucin-producing epithelium that resembled endocervical glands. Immunohistochemical staining was positive for estrogen receptor (ER) and mucin. Following a 6-week post-operative period, the patient has demonstrated abrupt complete recovery of symptoms.
Conclusion: An effective multidisciplinary approach, including macroscopic evaluation via cystoscopy and histopathological microscopic evaluation, excludes potential malignancy mimickers. Surgical resection leads to complete resolution of symptoms.
Keywords: Bladder endocervicosis, Chronic pelvic pain, Dysuria, Müllerianosis of the urinary bladder
Medical imaging acknowledgement. Dr. Oleg Mironov, MD, FRCPC, Department of Medical Imaging, McMaster University, Hamilton, Ontario.
Author ContributionsMoaz Alowami - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Oluwaseun Adelekan - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Lorraine Min-Shan Liang - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Pooja Vasudev - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionDr. Pooja Vasudev is the guarantor of submission and accepts full responsibility for the integrity of the work, had access to all the data in the study, and controlled the decision to publish.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2026 Moaz Alowami et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.