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Case Report
Breast implant associated anaplastic large cell lymphoma: Case report and review
1 Professor of Faculty of Medicine, Department of Internal Medicine, University of Brasília, Brasília-DF, Brazil
2 Medical Doctor, Department of Hematology, CETTRO-Center of Cancer of Brasilia, Brasília-DF, Brazil
3 Medical Academic, Department of Internal Medicine, University of Brasília, Brasília-DF, Brazil
Address correspondence to:
Flávia Zattar Piazera
Faculty of Medicine, University of Brasília, SQS 109, Block E, apartment 616, Brasília-DF 70372-50,
Brazil
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Article ID: 101484Z01FP2024
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Piazera FZ, Pereira PHM, Athaide LHR, de Sá Vasconcelos R. Breast implant associated anaplastic large cell lymphoma: Case report and review. Int J Case Rep Images 2024;15(2):126–130.ABSTRACT
Breast implant associated-anaplastic large cell lymphoma (BIA-ALCL) is a recent neoplasia that affects the mammary capsule. In an objective way, data supports that 1 in 6,972 breast implants will evolve annually to BIA-ALCL, which is classified as a rare type of non-Hodgkin lymphoma with no clear physiopathology established. The most common symptoms are preprosthetic late seroma, tumoral mass, lymphadenopathy, and skin alterations. The diagnosis is based on evaluation with imaging, such as ultrasonography and magnetic resonance image (MRI). The gold standard diagnosis is histopathologic analysis of aspirated fluid. Treatment is focused on excision or radiotherapy combined with chemotherapy and immunotherapy, based on the staging of the tumor. We describe a 57-year-old female who developed BIA-ALCL 16 years after bilateral silicone prosthesis implantation with the initial presentation of recurring seroma.
Keywords: Anaplastic large cell lymphoma, Breast implant, Lymphoma, Neoplasms
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Acknowledgments
The authors would like to thank the medical team at the CETTRO Cancer Treatment Center for their assistance and collaboration in supporting scientific production.
Author ContributionsFlávia Zattar Piazera - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pedro Henrique Medeiros Pereira - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Luis Henrique Ramos Athaide - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Rafael de Sá Vasconcelos - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Flávia Zattar Piazera et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
