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Case Report
Could tractography help in the diagnosis of motor neuron diseases\amyotrophic lateral sclerosis? A case report
1 Medical student at Iguaçu University - UNIG/RJ, Nova Iguaçu - RJ, Brazil
2 Physician, Neurologist, Adjunct Professor of Medicine at Universidade Iguaçu - UNIG/Nova Iguaçu, RJ, Brazil
3 Neuroradiologist, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro - RJ, Brazil
4 Department of Neurology of Hospital Geral de Nova Iguaçu, PhD student in Neurology at the Federal University of the State of Rio de Janeiro - UNIRIO, Adjunct Professor of Medicine at Iguaçu University - UNIG/Nova Iguaçu, RJ, Brazil
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Antonio Marcos da Silva Catharino
Rua Gavião Peixoto 70, Room 811, CEP 24.2230-100, Icaraí, Niterói-RJ,
Brazil
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Article ID: 101418Z01FF2023
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Felicio FC, Campos MB, Neves MAO, Pereira DA, Toomassini LAB, da Silva Catharino AM. Could tractography help in the diagnosis of motor neuron diseasesamyotrophic lateral sclerosis? A case report. Int J Case Rep Images 2023;14(2):97–101.ABSTRACT
Introduction: Amyotrophic lateral sclerosis (ALS) is a disease that affects motor neurons, progressively degenerating them. This degeneration process has a complex and multifactorial etiology, culminating in the motor disability of the carriers.
Case Report: The case report discusses a clinical suspicion of motor neuron disease (ALS) in the patient NVF, male, 72 years old, with a report of falls and paresis in the left distal crural third for two years. His condition evolved with the four limbs and trunk involvement, but it does not show bulbar involvement. In addition, atrophy, fasciculations, and paresis have been identified from lower motor neuron injury in all four limbs. Regarding the pyramidal pathway, only lively but symmetrical reflexes.
Conclusion: In the last two decades, there have been significant advances in non-invasive imaging techniques, which allow the evaluation of brain structure, as is the case with tractography. Although this technique does not diagnose ALS, it can help early detection.
Keywords: ALS amyotrophic lateral sclerosis, Motor neuron diseases, Tractography
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Author Contributions
Felipe de Castro Felicio - Substantial contributions to conception and design, Interpretation of data, Drafting the article, Final approval of the version to be published
Marcello de Brito Campos - Substantial contributions to conception and design, Interpretation of data, Drafting the article, Final approval of the version to be published
Marco Antônio Orsini Neves - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Daniel Antunes Pereira - Substantial contributions to conception and design, Interpretation of data, Drafting the article, Final approval of the version to be published
Lara Alexandre Brandão Toomassini - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Antonio Marcos da Silva Catharino - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Felipe de Castro Felicio et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
