Case Report


A novel clinical protocol for dentin hypersensitivity management based on regenerative dental gel associated with calcium: A case study in a patient with periodontal disease

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1 Student, Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil

2 Graduating, Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil

3 Doctor, Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil

Address correspondence to:

Leandro Araújo Fernandes

Universidade Federal de Alfenas – UNIFAL-MG, Rua Gabriel Monteiro da Silva, 700, Centro, CEP: 37130-001, Alfenas, MG,

Brazil

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Article ID: 101386Z01AR2023

doi: 10.5348/101386Z01AR2023CR

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How to cite this article

Reis ALM, dos Reis MC, Mazzola T, da Cruz Pegoraro JV, de Lima DC, Fernandes LA. A novel clinical protocol for dentin hypersensitivity management based on regenerative dental gel associated with calcium: A case study in a patient with periodontal disease. Int J Case Rep Images 2023;14(1):70–74.

ABSTRACT


Introduction: Dentin hypersensitivity (DH) is defined as pain caused by dentin exposure in response to various stimuli. Patients with periodontal disease (PD) frequently report DH due to root surface exposure or after periodontal treatment. Bioactive agents derived from calcium and/or silicon-based systems, such as REFIX technology, have been used to promote tooth regeneration, with focus on tooth sensitivity treatment.

Case Report: Based on this, the efficacy of REFIX gel combined with calcium on the treatment of a DH was evaluated in a PD 45-year-old male patient. The patient’s right and left sides were randomly selected to use one of the prophylaxis dental protocols: REFIX dental gel/calcium (RDGCa) (experimental: 13, 14, 15 teeth) or Pumice Stone (PS) (control: 23, 24, 25 teeth). The products were applied using dental polishing brush during 10 seconds in each tooth surface. Schiff Air Index (SAI) for sensitive teeth (0–3) were performed by applying air jet to each tooth’s vestibular surface for 5 seconds after and before the prophylaxis. The patient reported pain and interruption of the stimulus before and after PS prophylaxis (SAI 3 and 3 respectively). There was a reduction in pain when RDGCa protocol was used (SAI 3—before/SAI 1—after). In this instance, the patient felt the stimulus but did not request to be interrupted. This contrasted with the outcomes of the initial stimulus as well as PS.

Conclusion: The results showed that the RDGCa strategy was successful in lowering DH in PD patients.

Keywords: Bioactive agents, Dental regeneration, Dentin hypersensitivity, Desensitizing agents, Periodontal disease

SUPPORTING INFORMATION


Acknowledgments

The authors are grateful for the support of Trials—Oral Health and Technologies for making the product used for the study available.

Author Contributions

Ana Luiza Marques Reis - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Marcela de Cássia dos Reis - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Thamires Mazzola - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

João Vitor da Cruz Pegoraro - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Daniela Coelho de Lima - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Leandro Araújo Fernandes - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guarantor of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2023 Ana Luiza Marques Reis et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.