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Case Report
A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor
1 Assistant Professor of Medicine, Department of Interdisciplinary Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida, USA
2 Oncologic Surgical Pathology Fellow, Department of Pathology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida, USA
3 Chair of Medicine, Associate Professor of Medicine, Department of Interdisciplinary Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida, USA
Address correspondence to:
Jacqueline Wesolow
Assistant Professor of Medicine, Department of Interdisciplinary Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida 33612,
USA
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Article ID: 101076Z01JW2019
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How to cite this article
Wesolow J, Allen N, Ramsakal A. A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor. Int J Case Rep Images 2019;10:101076Z01JW2019.ABSTRACT
Introduction: Sarcoidosis is often an overlooked differential diagnosis in many disease processes. It is a nonspecific inflammatory disease marked by granulomas. Being nonspecific makes it a more difficult disease to diagnose. It is a challenging diagnosis as it is a great mimicker of many other conditions and therefore missed. The finding of a granuloma is not specific for sarcoidosis as other disorders may present with granulomas. It is an important differential to keep in mind because of significant morbidity and mortality associated with this disease.
Case Report: Here we present a case of a female patient with vision loss and an intracranial mass. The mass was initially thought to be cancer and hence referred to our Cancer Center for further evaluation and workup. Upon biopsy the mass was diagnosed as sarcoidosis. She had no other systemic involvement at time of diagnosis. What makes this case of sarcoidosis rare is her solitary optic nerve involvement.
Conclusion: Sarcoidosis is a more difficult disease to diagnose than other diseases, such as coronary artery disease, hyperlipidemia, and diabetes as these diseases have very specific, easily accessible laboratory values, and imaging modalities for fairly quick and simple testing. These disorders rely on hemoglobin A1C, electrocardiograms, troponin values, cholesterol level, which, unlike sarcoidosis testing, are relatively inexpensive and disease specific. This case report highlights an unusual presentation of sarcoidosis and reminds the physician to not forget this in the differential diagnosis.
Keywords: Cancer, Granuloma, Ocular sarcoidosis, Sarcoidosis
SUPPORTING INFORMATION
Author Contributions
Jacqueline Wesolow - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nichole Allen - Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Asha Ramsakal - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Jacqueline Wesolow et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
