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Case Report
Hyperemesis gravidarum with acute liver injury and positive feto-maternal outcome
1 PGY-3, Family Medicine Department, of The Brooklyn Hospital Center, Brooklyn, New York, United States
2 Attending Physician, Family Medicine Department, of The Brooklyn Hospital Center, Brooklyn, New York, United States
3 International Medical Graduate, M.D. Candidate ’19, Brooklyn, New York, United States
4 St. George’s University School of Medicine, M.D. Candidate ’19, Brooklyn, New York, United States
Address correspondence to:
Ricardo Alonso
MD, 66 Saint Paul Place Apt 6F, Brooklyn, New York 11226,
United States
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Article ID: 100983Z01RA2018
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How to cite this article
Alonso R, Prabhjot M, Gonzalez A, Rosen E, Wolfe D. Hyperemesis gravidarum with acute liver injury and positive feto-maternal outcome. Int J Case Rep Images 2018;9:100983Z01RA2018.ABSTRACT
This is a case report of Hyperemesis Gravidarum (HG) with a distinctly abnormal elevated ALT and AST values, in association with intractable nausea and vomiting. A 26-year-old woman G2P1A0 with a 9-week gestational age and no significant past medical history, presented with intractable nausea and vomiting despite medication use for three weeks. Despite administration of Vitamin B6, the symptoms persisted. During this period, the patient was unable to tolerate solids or liquids, and experienced progressive weakness, fatigue, and non-radiating epigastric pain. The patient was admitted to the Brooklyn Hospital Center Family Medicine service and found to have notable electrolyte disturbances, and remarkable transaminitis, with alanine aminotransferase (ALT) and aspartate aminotransferase (AST) values of 3400 IU/L and 717 IU/L respectively. All alternative diagnoses were ruled out. Ultimately, transaminitis resolved and mother an baby are doing well. This case report describes the typical clinical presentation of HG with acute liver injury and positive feto-maternal outcome.
Keywords: Acute liver injury, Benign transaminitis, Hyperemesis gravidarum, Pregnancy
SUPPORTING INFORMATION
Author Contributions
Ricardo Alonso - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Manes Prabhjot - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Anabel Gonzalez - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Elizabeth Rosen - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Danielle Wolfe - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this case report.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2018 Ricardo Alonso et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
