Introduction: Leiomyomas are benign, soft tissue tumors, arising from the smooth muscle. They usually affect the muscular layer of the gut and body of the uterus. Oral leiomyomas are extremely rare and are thought to arise from the smooth muscle wall of blood vessels. They present as slow growing, well-circumscribed, painless swellings accounting for only 0.42% of soft tissue neoplasms [1] of the oral cavity.
Case Report: A 14 years old boy presented to our department with a chief complaint of slow-growing mass since six months duration in the left hard palate. Based on the history, clinical, radiological and histopathological findings the mass was diagnosed as leiomyoma of hard palate. Immunohistochemistry was carried out for a more precise confirmation of the tumor, which showed positivity for SMA and vimentin. The mass was treated by extraction of the involved teeth followed by surgical excision of the tumor. No recurrence was noted during four month follow-up.
Conclusion: Oral leiomyomas are very rare, with low recurrence rates. These benign lesions respond well to surgical excision of tumor mass. In this paper, we present a case of leiomyoma of hard palate in a 14 years old boy, along with a brief note on review of literature on leiomyoma.

Keywords: Leiomyoma, Oral leiomyoma, Smooth muscle tumor, Hard palate tumor