Case Report
 
Severe rhabdomyolysis induced renal failure after influenza vaccination in a patient on statins therapy
Shu-Hua Chen1, Cheng-Jui Lin2, Tung-Ying Chen3
1MD, Division of Nephrology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
2MD, PhD, Division of Nephrology, Department of Internal Medicine, Mackay Memorial Hospital, 92 Chung San North Road, Section 2, Taipei 104, Taiwan.
3MD, Division of pathology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.

Article ID: Z01201703CR10775SC
doi:10.5348/ijcri-201736-CR-10775

Address correspondence to:
Cheng-Jui Lin
MD, PhD, Division of Nephrology, Department of Internal Medicine
Mackay Memorial Hospital, 92 Chung San North Road
Section 2, Taipei 104
Taiwan

Access full text article on other devices

  Access PDF of article on other devices

[HTML Full Text]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]


How to cite this article
Shu-Hua C, Cheng-Jui L, Tung-Ying C. Severe rhabdomyolysis induced renal failure in a patient after an influenza vaccination. Int J Case Rep Images 2017;8(3):205–208.


Abstract
Introduction: There are various causes leading to acute rhabdomyolysis, and the most common potentially lethal complication of rhabdomyolysis is acute kidney injury. Influenza vaccination-associated rhabdomyolysis with acute renal failure is rarely reported in literature. There are few data regarding kidney biopsy results from rhabdomyolysis induced renal failure after influenza vaccination.
Case Report: A 55-year-old male with chronic kidney disease stage 3a with hyperlipidemia under rosuvastatin control, who was admitted due to severe rhabdomyolysis induced renal failure after influenza vaccination. Kidney biopsy revealed acute tubular necrosis (ATN) and acute interstitial nephritis (AIN) superimposed on focal segmental glomerulosclerosis.
Conclusion: Our experience illustrates the dual pathologic findings of ATN and AIN, both induced by influenza vaccine in a patient with chronic kidney disease on statin therapy.

Keywords: Acute tubular interstitial nephritis, Influenza vaccination, Kidney biopsy, Renal failure, Rhabdomyolysis


[HTML Full Text]   [PDF Full Text]

Author Contributions
Shu-Hua Chen – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Cheng-Jui Lin – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Tung-Ying Chen – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Shu-Hua Chen et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.