Case In Images
 
Xanthogranulomatous cholecystitis: The great gallbladder carcinoma masquerader
Massimo Arcerito1, John Moon1, Kevin Tri Nguyen2
1MD, FACS Division of Inland Empire, Department of Surgery, University of California Irvine, Irvine CA.
2MD, PhD, FACS, Piedmont Healthcare, Transplant Institute, Atlanta, GA.

Article ID: Z01201703CI10021MA
doi:10.5348/ijcri-201703-CI-10021

Address correspondence to:
Massimo Arcerito
MD, FACS, Clinical Associate Professor, Division of Inland Empire, Department of Surgery
University of California Irvine
Irvine CA

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How to cite this article
Arcerito M, Moon J, Tri Nguyen K. Xanthogranulomatous cholecystitis: The great gallbladder carcinoma masquerader. Int J Case Rep Images 2017;8(3):222–226.


Abstract
Introduction: Xanthogranulomatous chole-cystitis represents an uncommon chronic cholecystitis characterized by gallbladder wall thickening infiltrating to the adjacent liver parenchyma. This feature creates a challenge for the hepatobiliary surgeon in treating this rare disease, which mimics gallbladder carcinoma leading to unnecessary enlarged hepatic resection.
Case Report: A 62-year-old male presenting at emergency department complaining of eight weeks history of right upper quadrant pain, nausea, with intermittent vomiting and severe weight loss. Surgical consultation was obtained. All imaging workup, including conventional abdominal ultrasound, computed tomography scan of the abdomen and pelvis, magnetic resonance imaging scan of the abdomen and positron emission tomography scan suggested gallbladder carcinoma. He underwent extended right hepatectomy, pancreaticoduodenectomy, with primary intrahepatic Roux-Y hepaticojejunostomy. The hospital course of patient was unremark-able being discharged six days after surgery. Final pathology was compatible with xanthogranulomatous cholecystitis.
Conclusion: This rare entity can lead the hepatobiliary surgeon to face a challenge and sometime useless surgical treatment which might provoke morbidity and mortality to the patient. More define clinical and radiographic criteria are needed in diagnosing and treating xanthogranulomatous cholecystitis, which must be labeled as the great gallbladder carcinoma masquerader.

Keywords: Contrast enhancing ultrasound, Foamy cells, Pancreaticoduodenectomy, Xanthogranulomatous cholecystitis


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Author Contributions
Massimo Arcerito – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
John Moon – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Kevin Tri Nguyen – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Massimo Arcerito et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.