Case Report
 
Hypertrophic obstructive cardiomyopathy in the setting of systemic scleroderma
Robert Sogomonian1, Hassan Alkhawam1, Feras Zaiem2, Sunyoung Lee1, M. Umair Bakhsh3, Emma A. Moradoghli Haftevani4, Dennis Chang5
1Department of Medicine, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, New York, USA.
2Mayo Evidence Based Practice Center- Mayo Clinic, Rochester, MN.
3Department of Medicine, Mount Sinai St. Luke's Hospital, NYC, NY, USA.
4Ross University School of Medicine.
5Department of Medicine, Icahn School of Medicine at Mount Sinai, NYC, USA.

doi:10.5348/ijcri-2015116-CR-10577

Address correspondence to:
Robert Sogomonian
MD, Department of Medicine
Elmhurst, Hospital, Center Icahn School of Medicine at Mount Sinai
7901 Broadway, Elmhurst, New York 11373
USA

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How to cite this article
Sogomonian R, Alkhawam H, Zaiem F, Lee S, Bakhsh MU, Haftevani EAM, Chang D. Hypertrophic obstructive cardiomyopathy in the setting of systemic scleroderma. Int J Case Rep Images 2015;6(11):717–719.


Abstract
Introduction: The association of systemic sclerosis (SS) with restrictive cardiomyopathy has well been established, but that with hypertrophic obstructive cardiomyopathy (HOCM) is not clearly understood. Herein, we report a case of a patient with SS, identified to have both HOCM and myocardial fibrosis.
Case Report: A 54-year-old female with systemic sclerosis, idiopathic lung disease with moderate pulmonary hypertension, presented with fatigue, decreased appetite and shortness of breath. Cardiac magnetic resonance imaging (CMRI) was significant for both hypertrophic and restrictive cardiomyopathy. Cardiac biopsy revealed evidence of diffuse fibrosis.
Conclusion: Our case report describes an interesting association between SS and HOCM, as well as restrictive cardiomyopathy. However, more evidences are needed to clarify whether this unique affiliation is a coincidental random finding or a causative association.

Keywords: Cardiac biopsy, Cardiomyopathy, Hypertrophic obstructive cardiomyopathy (HOCM), Lung disease, Pulmonary hypertension, Systemic sclerosis (SS)


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Author Contributions
Robert Sogomonian – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hassan Alkhawam – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Feras Zaiem – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sunyoung Lee – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
M. Umair Bakhsh – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Emma A. Moradoghli Haftevani – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Dennis Chang – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Robert Sogomonian et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.