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Case Report
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| Anaphylaxis and Kounis syndrome after using amoxicillin and clavulanic acid | ||||||
| Gokhan Eyupoglu1, Mehmet Tatli1, Kerem Dost Bilmez2, Ozlem Guneysel2 | ||||||
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1MD, Emergency Medicine, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.
2MD, Associate Professor, Emergency Medicine, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey. | ||||||
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| How to cite this article |
| Eyupoglu G, Tatli M, Bilmez KD, Guneysel O. Anaphylaxis and Kounis syndrome after using amoxicillin and clavulanic acid. Int J Case Rep Images 2015;6(4):207–210. |
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Abstract
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Introduction:
Kounis syndrome is the fortuitous occurrence of acute coronary syndrome consisting of hypersensitivity reactions related to allergic or hypersensitivity activation of inflammatory cells.
Case Report: An 84-year-old male admitted to our emergency department with anaphylaxis symptoms after his intake of a 1000 mg amoxicillin and clavulanic acid (ACA) tablet. Diabetes, coronary artery disease and hypertension had been encountered in the patient's medical history. During the physical examination, uvula edema, wheezing, rales and rhonchi were present. Adrenaline, pheniramine and methylprednisolone were given to the patient with a diagnosis of anaphylaxis. During his observation, ECG changes and troponin elevation were detected and he was diagnosed as type 2 Kounis syndrome. After 24 hours follow-up, he was discharged without any complication. Conclusion: A single dose of ACA can cause anaphylaxis and may result in Kounis syndrome. It should be taken into consideration in all types of allergic reactions which treated by adrenaline. | |
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Keywords:
Anaphylaxis, Clavulanic acid, Coronary syndrome, Drug allergy, Kounis syndrome
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Author Contributions
Gokhan Eyupoglu – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Mehmet Tatli – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published Kerem Dost Bilmez – Conception and design, Drafting the article, Critical revision of the article, Final approval of the version to be published Ozlem Guneysel – Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Gokhan Eyupoglu et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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About The Authors
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