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Case Series
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| Isolated polyostotic fibrous dysplasia of the spine: A diagnostic challenge | ||||||
| Virinder Mohan1, Krishnan K. Unni2, Nimisha Batra3, Ajit Ambekar4 | ||||||
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1MD, (Radiology), PhD, (Radiology), FICR, Post Graduate, Department of Radio-Diagnosis & Imaging, Subharti Medical College, Swami Vivekanand Subharti University, Subhartipuram, N.H 58 Meerut 250005 (UP), India. (Formerly Senior Consultant and Chief of Radiological Services, Armed Forces Hospital, Muscat (Sultanate of Oman).
2MD, Chief of Laboratory Medicine & Pathology, Mayo's Clinic, 200 First Street SW Rochester MN 55905, USA. 3MBBS, Resident, Post Graduate, Department of Radio-Diagnosis & Imaging, Subharti Medical College, Swami Vivekanand Subharti University, Subhartipuram, N.H 58 Meerut 250005 (UP), India. 4MS, Ortho, Consultant Orthopaedic Surgeon, Armed Forces Hospital, Muscat (Sultanate of Oman). | ||||||
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| How to cite this article |
| Mohan V, Unni KK, Batra N, Ambekar A. Isolated polyostotic fibrous dysplasia of the spine: A diagnostic challenge. Int J Case Rep Images 2014;5(12):808–812. |
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Abstract
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Introduction:
Fibrous dysplasia is a non-malignant fibro-osseous disease of the bone can occur in monostotic or polyostotic form. The polyostotic form is more common and involves pelvis, femur, tibia, ribs, calvarium and the facial bones. Spinal involvement in fibrous dysplasia is extremely uncommon both in mono-ostotic as well as in polyostotic variety. Isolated involvement of multiple vertebrae with normal rest of the skeleton is extremely rare and only one such case has been reported earlier [1].
Case Series: In this study, we are reporting two cases of isolated fibrous dysplasia of the spine with multiple vertebral involvement and without any clinical, endocrinal as well as radiological evidence of the disease in the axial skeleton. The patients presented in 2nd–4th decade, both with complaints of low back pain. The radiological, clinical and biochemical evaluation have been discussed in details. The diagnosis of the disease was made in both cases on the basis of clinico-radiological workup and confirmed by histopathology. Conclusion: Fibrous dysplasia is not commonly seen to occur in spinal column. When seen, vertebral lesions show almost the same features on conventional radiographs as seen in appendicular skeleton. Patients usually present with minor clinical symptoms which are disproportionate to the imaging findings. A high index of suspicion on the conventional radiography with proper clinical workup will help in the diagnosis. | |
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Keywords:
Fibrous dysplasia, Fibrous dysplasia of spine, Isolated spinal fibrous dysplasia
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Author Contributions:
Virinder Mohan – Substantial contribution to concept and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Krishnan K. Unni – Substantial contribution to concept and design, Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published Nimisha Batra – Substantial contribution to concept and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Ajit Ambekar – Substantial contribution to concept and design, Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2014 Virinder Mohan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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