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Case Report
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| Isolated plexiform neurofibroma presenting as white lesion of vulva: A case report | ||||||
| Sunita Arora1, Rupneet Kaur2, Poonam Goel3, RPS Punia4 | ||||||
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1Assistant Professor, Department of OBS and Gynaecology, Govt Medical College and Hospital, Chandigarh, India.
2Senior Resident, Department of OBS and Gynaecology, Govt Medical College and Hospital, Chandigarh, India. 3Professor, Department of OBS and Gynaecology, Govt Medical College and Hospital, Chandigarh, India. 4Department of Pathology, Government Medical College & Hospital (GMCH), Sector-32, Chandigarh, India. | ||||||
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| How to cite this article |
| Arora S, Kaur R, Goel P, Punia RPS. Isolated plexiform neurofibroma presenting as white lesion of vulva: A case report. Int J Case Rep Images 2014;5(7):505–508. |
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Abstract
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Introduction:
Neurofibromas commonly involve peripheral nervous system but rarely may involve genital organs such as labia, clitoris, vulva, vagina and cervix.
Case Report: We present a case of isolated plexiform neurofibroma of vulva which presented as white lesion of vulva. A tissue biopsy was done and the histopathological analysis-demonstrated plexiform neurofibroma with spindle shaped cells with wavy nuclei and bland nuclear chromatin. The immunohistochemical staining showed strong positivity for S-100 protein which has a strong correlation with neurofibromatosis-1. No systemic sign of neurofibromatosis was found. Conclusion: Plexiform neurofibroma may present as isolated white lesion of the vulva without any systemic involvement in the form of neurofibromatosis. So a tissue biopsy is mandatory for definitive diagnosis of any white lesion of vulva. | |
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Keywords:
Vulva, White lesion, Plexiform neurofibroma
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Author Contributions
Sunita Arora – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Rupneet Kaur – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published Poonam Goel – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published RPS Punia – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2014 Sunita Arora et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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