Case Series
 
Proliferative vitreoretinopathy secondary to degenerative retinoschisis: A case series
Mansvkhlal Amer1, Safia Ahmed2, Carpi Olali3, Sohail Ahmed4, Gupta M5
1Junior Doctor in Ophthalmology, Pilgrim Hospital, Boston. United Kingdom.
2Junior Doctor in Ophthalmology, Royal Blackburn Hospital Blackburn, United Kingdom.
3Ophthalmic Surgeon, Pilgrim Hospital, Boston, United Kingdom, Special Interest: Glaucoma and Neuro-Ophthalmology.
4Consultant Ophthalmic Surgeon, Pilgrim Hospital, Boston, United Kingdom, Special Interest: Strabismus and Vitreoretinal Surgery.
5Consultant Ophthalmic Surgeon, Pilgrim Hospital, Boston, United Kingdom, Special Interest: Glaucoma and Cataract.

doi:10.5348/ijcri-201454-CS-10040

Address correspondence to:
Carpi Akikio Olali
Department of Ophthalmology, Pilgrim Hospital
Sibsey Road, Boston
PE21 9QS, United Kingdom
Email: akikio771@hotmail.com

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How to cite this article
Amer M, Ahmed S, Olali C, Ahmed S, Gupta M. Proliferative vitreoretinopathy secondary to degenerative retinoschisis: A case series. International Journal of Case Reports and Images 2014;5(5):329–333.


Abstract
Introduction: We report two cases proliferative vitreoretinopathy that occurred as complication of degenerative retinoschisis.
Case Series: Two patients; a male and a female with vitreo-retinal hemorrhage seen in our clinic were evaluated and retinoschisis found as the only cause of the bleeding. Both were treated with Argon barrier photocoagulation which arrested the hemorrhage and resolved the visual symptoms.
Conclusion: It has been suggested that retinal ischemia occurs in retinoschisis and this triggers upregulation of growth factors and subsequent formation of new vessels. This hypothesis would need to be tested to ascertain the particular growth factors, that trigger this process and if other cytokines and interleukins also play a role as the process is a vitreoretinpathy.

Keywords: Retinoschisis, Vitreous hemorrhage, Growth factors, Vitreoretinopathy


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Author Contributions:
Mansvkhlal Amer – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Safia Ahmed – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Carpi Olali – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sohail Ahmed – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Gupta M – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
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The corresponding author is the guarantor of submission.
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Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Mansvkhlal Amer et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.