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Case Report
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| Benign reactive lesion with atypical mitosis: New example of an old story | ||||||
| Hua Zhong1, 2, Marina Chekmarva1, 2, Malik Deen2, Michael May2, Steven Deak3, Nicola Barnard2 | ||||||
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1MD, PhD, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States.
2MD, Department of Pathology and Laboratory Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States. 3MD, Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States. | ||||||
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| How to cite this article: |
| Zhong H, Chekmareva M, Deen M, May M, Deak S, Barnard N. Benign reactive lesion with atypical mitosis: New example of an old story. International Journal of Case Reports and Images 2014;5(3):235–239. |
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Abstract
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Introduction:
Ischemic fasciitis (atypical decubital fibroplasia) is a benign reactive lesion that may mimic mesenchymal malignancy. Atypical mitosis has never been reported in such a lesion, which adds an additional challenge to differential diagnosis.
Case Report: A 94-year-old chronically immobile and debilitated female presented with a slightly painful and rapidly growing mass over her right back. Based on the clinical and histological features of the lesion, the diagnosis of ischemic fasciitis, a benign reactive lesion of the deep dermis, was made. Active mitosis and atypical mitotic figures were demonstrated in the lesion. Conclusion: Ischemic fasciitis may show atypical mitotic figures that can mislead differential diagnosis. | |
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Keywords:
Ischemic fasciitis, Atypical decubital fibroplasia, Atypical mitosis, Soft tissue
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Author Contributions
Hua Zhong – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Marina Chekmareva – Substantial contributions to Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published Malik Deen – Substantial contributions to Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published Michael May – Substantial contributions to Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published Steven Deak – Substantial contributions to Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published Nicola Barnard – Substantial contributions to Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Hua Zhong et al. 2014; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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