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Case Report
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| Stroke in pregnancy: A rare case of protein C and protein S deficiency | ||||||
| Snigdha Kumari1, Ashok Kumar Biswas2, Sukanta Misra3 | ||||||
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1MBBS, MS. Resident, Department of Obstetrics and Gynecology.Vivekananda Institute of Medical Sciences, Ramakrishna Mission SevaPratishthan.Kolkata, West Bengal, India.
2MBBS, MD, DNB.Associate Professor, Department of Obstetrics and Gynecology.Vivekananda Institute of Medical Sciences, Ramakrishna Mission SevaPratishthan.Kolkata, West Bengal, India. 3MBBS, MD, FICMCH.Professor, Department of Obstetrics and Gynecology. Vivekananda Institute of Medical Sciences, Ramakrishna MissionSevaPratishthan. Kolkata, West Bengal, India. | ||||||
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| How to cite this article |
| Kumari S, Biswas AK, Misra S. Stroke in pregnancy: A rare case of protein C and protein S deficiency. International Journal of Case Reports and Images 2014;5(3):225–228. |
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Abstract
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Introduction:
Stroke in pregnancy is a rare occurrence, its reported incidence being 11–26 deliveries per 100,000. Ischemic strokes are slightly more common than hemorrhages. Subarachnoid hemorrhage, embolism and cerebral venous thrombosis can also occur, albeit with a lesser incidence. Peak incidence of stroke is in the peripartum and postpartum period. Mortality rate of pregnancy associated stroke is 10.13%. Therefore, rapid recognition and management of these patients are imperative to ensure successful outcome. We report a rare case of stroke during pregnancy which has the protein C and protein S deficiency as its precipitating cause.
Case Report: We report a case of a 24-year-old female, with previous cesarean section in her third trimester, suddenly developed weakness of left side of the body and deviation of face to the right. There was no history of head trauma, fever, unconsciousness or seizure. She did not have any skin rash, arthritis or signs of deep vein thrombosis. There was no history of prior fetal loss. Protein C and protein S levels were low. Conclusion: We report a rare case of stroke during pregnancy which has the protein C and protein S deficiency as its precipitating cause. Stroke is a recognized complication of pregnancy, is uncommon but feared. Stroke in young adults aged 15–35 years is more common in women with poorer outcome in terms of disability and dependence. Most pregnancy related stroke occurs in peripartum and puerperium. | |
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Keywords:
Stroke, Pregnancy, Protein C deficiency, Protein S deficiency
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Author Contributions
Snigdha Kumari – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Ashok Kumar Biswas – Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Sukanta Misra – Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Snigdha Kumari et al. 2014; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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About The Authors
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