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Case Report
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| Gastric malignancy presenting as adrenal insufficiency: A case report | ||||||
| Harsh Vardhan Tevethia1, Baskaran S2, Tony Mathew Kadavanu1, Riyaz M Panchbhaya3, Sunny DAN1, Siva PK3 | ||||||
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1M.B.B.S, Resident, Department of Internal Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, Puducherry, India.
2M.B, D.N.B, Consultant physician, Department of Internal Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, Puducherry, India. 3M.B, M.D, Assistant Professor, Department of Internal Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, Puducherry, India. | ||||||
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| How to cite this article: |
| Tevethia HV, Baskaran S, Kadavanu TM, Panchbhaya RM, Dan S, Siva PK. IGastric malignancy presenting as adrenal insufficiency: A case report. International Journal of Case Reports and Images 2013;4(12):705–708. |
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Abstract
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Introduction:
Carcinomas in the lung, breast, and lymphomas are known to metastasize to the adrenal gland. However, these metastases initially do not present with signs and symptoms of adrenal insufficiency leading to a decreased chance of adrenal insufficiency being diagnosed. We report a case of adrenal insufficiency due to bilateral adrenal metastases as the presenting manifestation of gastric carcinoma.
Case Report: A 72-year-old male was admitted to our hospital due to altered mental status, weakness, anorexia, hematemesis and urinary incontinence for three days. Hyponatremia, hyperkalemia, anemia, and mild metabolic acidosis were detected. A diagnosis of gastric carcinoma along with bilateral metastases of the adrenal glands was made after biopsy computed tomography and positron emission tomography scans. Initiation of mineralocorticoid replacement therapy, improved the condition of patient. Conclusion: There are only a few reports of adrenal insufficiency or true Addisonian crisis being the presenting manifestation of underlying malignant tumors of the lung, colon, or lymphomas. One should also consider the possibility of malignancy as a differential in such cases. | |
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Keywords:
Adrenal insufficiency, Gastric malignancy, Hyponatremia, Addison’s disease
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Author Contributions
Harsh Vardhan Tevethia – Acquisition of data, Critical revision of the article, Final approval of the version to be published Bhaskaran S – Conception and design, Critical revision of the article, Final approval of the version to be published Kadavanu Tony Mathew – Conception and design, Acquisition of data, Drafting the article, Critical revision of the article, Final approval of the version to be published Panchbhaya Riyaz – Analysis and interpretation of data, Drafting the article, Final approval of the version to be published Sunny DAN – Conception and design, Drafting the article, Critical revision of the article, Final approval of the version to be published SIva P K – Conception and design, Critical revision of the article, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© Harsh Vardhan Tevethia et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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