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Effect of Crocus sativus and its active compounds for the treatment of several diseases: A review
Rafie Hamidpour1, Soheila Hamidpour2, Mohsen Hamidpour3, Mina Shahlari4
1PhD, President, Pars Bioscience, Leawood, Kansas, United States.
2MD, Pars Bioscience, Leawood, Kansas, United States.
3PhD, Pars Bioscience, Leawood, Kansas, United States.
3BA, Pars Bioscience, Leawood, Kansas, United States.

doi:10.5348/ijcri-2013-12-407-RA-1

Address correspondence to:
Rafie Hamidpour
Pars Bioscience LLC
14109 Cambridge Lane
Leawood, Kansas
United States 66224
Phone: (913) 432-0107
Fax: (913) 432-5708
Email: rafi@parsbioscience.com

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How to cite this article:
Hamidpour R, Hamidpour S, Hamidpour M, Shahlari M. Effect of Crocus sativus and its active compounds for the treatment of several diseases: A review. International Journal of Case Reports and Images 2013;4(12):666–670.


Abstract
Introduction: The purpose of this article is to use literature search engines such as PubMed and SciFinder to locate scholarly journal articles pertaining saffron, its preparation, analysis, and its use in cancer treatments. Saffron comes from the dried red stigmas of the Crocus sativus L. flower. Along with its use in cooking and in traditional medicine, it has numerous applications as an antitoxic, anti-oxidant, and anti-cancer agent, due to its secondary metabolites and their derivatives are safranal, crocins, crocetin and dymethyl-crocetin. This study demonstrate that Crocus sativus extract (CSE) and its major constituents, crocin, and crocetin, significantly inhibited the growth of certain cancer cells while not effecting normal cells. Crocus sativus L. extract should be investigated further as a viable agent in the treatment of prostate, pancreatic or other types of cancer.

Keywords Crocus sativus L., Tumor inhibitor, Saffron components, Nutritional supplements

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Author Contributions
Rafie Hamidpour – Conception and design, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Soheila Hamidpour – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Mohsen Hamidpour – Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Mina Shahlari – Conception and design, Critical revision of the article, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© Rafie Hamidpour et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)