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Case Report
 
An unusual case of a bicuspid aortic valve and non-compaction of the left ventricle
Abdullah Omar1, George Stoupakis2
1MD, PGY-1, Department of Medicine, Georgia Health Sciences University, Augusta, GA.
2MD, Interventional Cardiologist, Department of Medicine, Hackensack University Medical Center, Hackensack, NJ.

doi:10.5348/ijcri-2013-05-312-CR-9

Address correspondence to:
George Stoupakis
MD, 30 Prospect Ave
Hackensack
NJ 07601
USA
Phone: (201) 343 - 7001
Email: gstoupakis@yahoo.com

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How to cite this article:
Omar A, Stoupakis G. An unusual case of a bicuspid aortic valve and non-compaction of the left ventricle. International Journal of Case Reports and Images 2013;4(5):279–282.


Abstract
Introduction: Myocardial noncompaction is thought to be a rare genetic disorder of myocardial morphogenesis.
Case Report: We report the case of a 22-year-old male with left ventricular noncompaction, bicuspid aortic valve and ascending aortic dilation. We discuss the genetic basis of myocardial noncompaction and potential etiologies that manifest in hyper-trabeculated myocardium in the presence or absence of extracardiac abnormalities.
Conclusion: Myocardial noncompaction is a rare genetic disorder thought to arise from disruption of normal organogenesis during development. Many genetic abnormalities have been associated with myocardial non-compaction. Recent research prompts the question of whether various genetic mutations exert their effect via a common pathway which manifest in similar morphological findings.

Keywords: Myocardial noncompaction, Bicuspid aortic valve, Myocardial morphogenesis, Genetics


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Author Contributions
Abdullah Omar – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published
Geroge Stoupakis – Substantial contributions to conception and design, Drafting the article, revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© Abdullah Omar et al. 2013; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)