Table of Contents    
Case Report
 
Pyoderma gangrenosum – rare manifestation of crohn's disease in 14-year-old child: Case report
Ajay Damor1, Varsha Shah1, Lalit Nainiwal1, Bhadra Trivedi2, Rohit Agrawal2 Vaibhav Patel3
1Assisstant Professor, Department of Pediatrics, SBKS MIRC, Pipariya, Vadodara, Gujarat, India.
2Third Year Pediatrics Resident, Department of Pediatrics, SBKS MIRC, Pipariya, Vadodara, Gujarat, India.
3Second Year Pediatrics Resident, Department of Pediatrics, SBKS MIRC, Pipariya, Vadodara, Gujarat, India.

doi:10.5348/ijcri-2012-08-166-CR-13

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How to cite this article:
Damor A, Shah V, Nainiwal L, Trivedi B, Agrawal R, Patel V. Pyoderma gangrenosum – rare manifestation of crohn's disease in 14-year-old child: Case report. International Journal of Case Reports and Images 2012;3(8):46–50.


Abstract
Introduction: Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, non-infective chronic inflammatory skin disorder of unknown etiology rarely affects children. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, hematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violaceous undermined borders. The diagnosis of pyoderma gangrenosum is clinical and depends on exclusion of other causes of cutaneous ulceration. The management of PG is treatment of underlying systemic medical illness and judicious use of immunosuppressant.
Case Report: A 14-year-old female child who presented with multiple ulcerative lesions all over body especially on leg, foot, arm, hand, scalp and face, with largest one on right leg. Associated complaints were fever, abdominal pain, diarrhea, fatigue, anorexia and weight loss. On examination; along with multiple ulcers, she had pallor and clubbing. Systemic examination revealed no abnormality except mild tenderness in right lumber region. On investigation she was diagnosed as Crohn's disease (CD) and treated with corticosteroid. On subsequent follow up visit she had symptomatic improvement and healed ulcers.
Conclusion: Pyoderma gangrenosum is rare manifestation of Crohn's disease in children. The diagnosis of PG is based on the typical clinical features and exclusion of other causes of ulcerative skin disorders and evaluation of systemic medical illness. The management is treatment of underlying systemic medical illness and judicious use of immunosuppressant.

Key Words: Pyoderma gangrenosum, Crohn's disease

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Author Contributions:
Ajay Damor – Conception and design, Drafting the article, Critical revision of the article, Final approval of the version to be published
Varsha Shah – Critical revision of the article, Final approval of the version to be published
Lalit Nainiwal – Drafting the article, Critical revision of the article, Final approval of the version to be published
Bhadra Trivedi – Conception and design, Drafting the article, Final approval of the version to be published
Rohit Agrawal – Conception and design, Drafting the article, Final approval of the version to be published
Vaibhav Patel – Conception and design, Drafting the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Ajay Damor et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)