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Case Report
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| Choroidal metastasis from breast cancer in a male patient treated successfully with systemic chemotherapy |
| Aymen Lagha1, Mouna Ayadi1, Leila Largueche2, Sarra Krimi1, Nesrine Chraiet1, Bassem Allani1, Hela Rifi1, Henda Raies1, Leila Elmatri2, Amel Mezlini1 |
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1Department of Medical oncology, Salah Azaiez Institute, Boulevard du 9 Avril, Bab Saadoun 1006 Tunis, Tunisia.
2Department of Ophthalmology B, Hedi Raies Institute, Boulevard du 9 Avril, Bab Saadoun 1006 Tunis, Tunisia. |
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doi:10.5348/ijcri-2012-07-141-CR-2
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Address correspondence to: Aymen Lagha, MD Department of Medical Oncology, Salah Azaiez Institute Boulevard du 9 avril Bab saadoun, 1006 Tunis Tunisia Phone: +21624440097 Email: aymen.lagha@hotmail.com |
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| How to cite this article: |
| Lagha A, Ayadi M, Largueche L, Krimi S, Chraiet N, Allani B, Rifi H, Raies H, Elmatri L, Mezlini A. Choroidal metastasis from breast cancer in a male patient treated successfully with systemic chemotherapy. International Journal of Case Reports and Images 2012;3(7):6–10. |
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Abstract
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Introduction:
To present a case of chemotherapeutic regression of metastasis of breast carcinoma to the choroid in a male patient.
Case Report: A 63-year-old male, with a past medical history of breast cancer, presented with blurred vision and progressive loss of visual acuity. Fundoscopy of the right eye revealed a choroidal mass in the upper temporal arcade associated with pigment epithelium impairment. Optic disc was normal and macular edema was not present. The patient was treated with systemic chemotherapy (epirubicin, cyclophosphamide, 5-fluorouracil), every three weeks, for six cycles. Five months into treatment, the patient reported a partial improvement in visual symptoms. A complete regression of the choroidal mass was noted with both magnetic resonance imaging and fundoscopy. Conclusion: In male as in female patients, breast carcinoma may metastasize to the choroid. Such metastasis must be suspected whenever a patient with a past history of breast cancer suffers from impaired vision. An In male as in female patients, breast carcinoma may metastasize to the choroid. Such metastasis must be suspected whenever a patient with a past history of breast cancer suffers from impaired vision. An appropriate ophthalmologic examination including fundoscopy should be performed. Treatment strategy is still based essentially on radiotherapy and should be modified individually depending on size, localization and presence of metastases to other organs and general condition of the patient. | |
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Key Words:
Breast cancer, Choroidal metastasis, Chemotherapy
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Author Contributions:
Aymen Lagha – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article and revising it critically for important intellectual content, Final approval of the version to be published Mouna Ayadi – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published Leila Largueche – Substantial contributions to analysis and interpretation of data, Drafting the article, Final approval of the version to be published Sarra Krimi – Substantial contributions to conception and design, Acquisition of data, Revising the article critically for important intellectual content, Final approval of the version to be published Nesrine Chraiet – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published Bassem Allani – Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published Hela Rifi – Substantial contributions to analysis and interpretation of data, Drafting the article, Final approval of the version to be published Henda Raies – Substantial contributions to analysis and interpretation of data, Drafting the article, Final approval of the version to be published Leila Elmatri – Substantial contributions to acquisition of data, Drafting the article, Final approval of the version to be published Amel Mezlini – Substantial contributions to conception and design, Acquisition of data, Revising the article critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission:
The corresponding author is the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
Authors declare no conflict of interest. |
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Copyright:
© Aymen Lagha et al. 2012; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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