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Case Report
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| Rapid diagnosis of sinonasal cancer in an anticoagulated patient: Outpatient clinical use of a gelatin-thrombin matrix (Floseal) for hemostasis following endonasal tumor biopsies |
| Shaun J Kilty1 |
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1Associate, Department of Otolaryngology-Head & Neck Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada.
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doi:10.5348/ijcri-2011-11-65-CR-3
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Address correspondence to: Shaun J Kilty Department of Otolaryngology – Head and Neck Surgery Room 242, 1053 Carling Avenue, Ottawa ON Canada. Phone: 1(613) 761-4030 Fax: 1(613) 729-2412 Email: shaunkilty@hotmail.com |
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| How to cite this article: |
| Kilty SJ. Rapid diagnosis of sinonasal cancer in an anticoagulated patient: Outpatient clinic use of a gelatin-thrombin matrix (Floseal) for hemostasis following endonasal tumor biopsies. International Journal of Case Reports and Images 2011;2(11):10-13. |
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Abstract
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Introduction:
The purpose of this case report is to describe the use of gelatin-thrombin matrix (Floseal) for hemostasis to control severe nasal bleeding following endonasal biopsies in an elderly patient receiving anticoagulant therapies.
Case Report: An 81-year-old woman with advanced Alzheimer's disease presented with rapid onset of midfrontal swelling, pain and orbital hypertelorism. Profuse bleeding occurred following tumor biopsies in the outpatient clinic which was controlled in less than five minutes with a single administration of Floseal. The pathologic diagnosis was diffuse large B-cell lymphoma and treatment was initiated within the week. There was no recurrence of bleeding following this single treatment. The use of Floseal safely and economically allowed for rapid diagnosis and treatment of this sinonasal cancer without the need to stop and restart anticoagulation therapy in an elderly patient with dementia. Conclusion: The outcome from the clinical management of this case suggests that this treatment approach may be a model for use in the rapid diagnosis of sinonasal pathology in the outpatient clinic even in the setting of anticoagulation. | |
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Key Words:
Floseal matrix, Hemostasis, Biopsy, Anticoagulants, Diagnosis, Warfarin, Aspirin, Paranasal sinuses
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Author Contributions:
Shaun J Kilty - Conception and design, acquisition of data and interpretation of data; Drafting the article and revising it critically for important intellectual content; Final approval of the version to be published |
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Guarantor of submission:
The corresponding author is the guarantor of submission. |
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Source of support:
None |
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Conflict of interest:
Support for Dr. Gage and her assistance with this publication was provided by Baxter Healthcare Corporation. |
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Copyright:
© Shaun J Kilty et. al. 2011; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.) |
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