Table of Contents    
CASE REPORT
 
Abnormal dynamics of growth hormone after thyrotropin-releasing hormone loading test, gonadotropin-releasing hormone loading test, and oral glucose tolerance test in mixed gonadal dysgenesis with a pituitary lesion
Akira Matsuno1, So Yamada1, Shoko M. Yamada1, Hiroshi Nakaguchi1, Katsumi Hoya1, Mineko Murakami1
1Department of Neurosurgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara City, Chiba 299-0111, Japan.

doi:10.5348/ijcri-2011-01-15-CR-3

Address correspondence to:
Akira Matsuno
Department of Neurosurgery
Teikyo University Chiba Medical Center
3426-3 Anesaki, Ichihara City, Chiba 299-0111, Japan
Phone: 81-436-62-1211 ext. 2621
Fax: 81-436-62-1357
E-mail: akirakun@med.teikyo-u.ac.jp

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How to cite this article:
Matsuno A, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M. Abnormal dynamics of growth hormone after thyrotropin-releasing hormone loading test, gonadotropin-releasing hormone loading test, and oral glucose tolerance test in mixed gonadal dysgenesis with a pituitary lesion. International Journal of Case Reports and Images 2011;2(1):12-14.


Abstract

Introduction: In mixed gonadal dysgenesis or X/XY gonadal dysplasia, the axis of hypothalamus-pituitary-reproductive organ is usually maintained.

Case Report: We report a 29-year-old woman of mixed gonadal dysgenesis with abnormal growth hormone (GH) dynamics after thyrotropin-releasing hormone loading test, gonadotropin-releasing hormone loading test, and oral glucose tolerance test and a pituitary lesion.

Conclusion: The abnormal dynamics of pituitary hormone, especially GH, and the existence of a pituitary lesion in mixed gonadal dysgenesis is a rare event.



Key Words: Mixed gonadal dysgenesis, X/XY gonadal dysplasia, Growth hormone, Amenorrhea, Silent pituitary somatotroph adenoma


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Author Contributions:
Akira Matsuno - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
So Yamada - Conception and design, Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Shoko M. Yamada - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Hiroshi Nakaguchi - Conception and design, Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Katsumi Hoya - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Mineko Murakami - Conception and design, Acquisition of data, Analysis and interpretation of data, Critical revision of the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
The author(s) declare no conflict of interests.
Copyright:
© Akira Matsuno et. al. 2011; This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)