Case Report


Revisiting pemphigus vulgaris: A case report and review of literature

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1 Assistant Professor, Department of Oral Pathology & Microbiology, Bharati Vidyapeeth Deemed to be University, Dental College & Hospital, Pune, India

2 Professor & Head, Department of Oral Pathology & Microbiology, Bharati Vidyapeeth Deemed to be University, Dental College & Hospital, Pune, India

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Revati Shailesh Deshmukh

Professor & Head, Department of Oral Pathology & Microbiology, Bharati Vidyapeeth Deemed to be University, Dental College & Hospital, Pune,

India

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Article ID: 101417Z01PD2023

doi: 10.5348/101417Z01PD2023CR

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How to cite this article

Deo PN, Deshmukh RS. Revisiting pemphigus vulgaris: A case report and review of literature. Int J Case Rep Images 2023;14(2):91–96.

ABSTRACT


Introduction: Pemphigus is an autoimmune blistering mucocutaneous disease. Production of auto-antibodies against desmosomal glycoproteins is a characteristic feature of the disease. Oral lesions of pemphigus vulgaris are many a times first sign of the disease and hence it is important for a dentist to be familiar with the clinical appearance, diagnosis, and treatment modalities.

Case Report: This report describes a case of pemphigus vulgaris in a female patient who presented with ulcers on the gingiva. On the basis of clinical examination and histopathology, we arrived at a diagnosis of pemphigus vulgaris, which was confirmed by immunofluorescence.

Conclusion: If left undiagnosed or untreated pemphigus vulgaris may be fatal. Early diagnosis will aid in appropriate treatment and better outcome of the disease.

Keywords: Acantholysis, Autoantibodies, Pemphigus, Tzanck cells

SUPPORTING INFORMATION


Author Contributions

Priya Nimish Deo - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Revati Shailesh Deshmukh - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guarantor of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2023 Priya Nimish Deo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.