Case Report
1 MD, Radiology Department, Ibn Sina Paediatric Teaching Hospital, Mohammed V University, Rabat, Morocco
2 MD, Professor, Radiology Department, Ibn Sina Paediatric Teaching Hospital, Mohammed V University, Rabat, Morocco
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Romeo Thierry Yehouenou Tessi
MD, Radiology Department, Ibn Sina Paediatric Teaching Hospital, Mohammed V University, BP 6527, Rabat,
Morocco
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Article ID: 101411Z01RT2023
Neurofibromatosis type 1 is a genetic disorder representing one of the most common forms of Von Recklinghausen’s disease. The neurofibromatoses are a group of heterogeneous, yet distinct, autosomal-dominant inherited neurogenetic disorders that include neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis. It is characterized by a large clinical polymorphism with the development of «café-au-lait» skin spots, benign tumors affecting the skin, peripheral nerves, optic pathway, and can involve the brain, bones, and vessels. We report the case of an 8-year-old child with neurofibromatosis type 1 diagnosis confirmed with clinical presentation and histological examination. He was referred for multidisciplinary management. There are clear diagnostic criteria according to a consensus (two or more criteria for diagnosis). The diagnosis is foremost clinical; the role of imaging is threefold: firstly, to confirm the diagnosis, secondly, to delineate extent of disease, and thirdly, suggests the type of the tumors in the affected patient. It helps to manage complications and follow-up. Histological examination confirms the diagnosis.
Keywords: Café-au-lait macules, CT scan, MRI, Neurofibroma, Neurofibromatosis 1
We thank the following individuals for their review of earlier drafts of the manuscript: Prof. Latifa Chat and Prof. Nazik Allali, chief service and deputy chief service of Radiology Department, Ibn Sina Paediatric Teaching Hospital, Mohammed V University, Rabat, Morocco.
Author ContributionsRomeo Thierry Yehouenou Tessi - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Chaimae Lahlou - Substantial contributions to conception and design, Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published
Soufiane Rostoum - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Siham El Haddad - Revising it critically for important intellectual content, Final approval of the version to be published
Nazik Allali - Revising it critically for important intellectual content, Final approval of the version to be published
Latifa Chat - Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Romeo Thierry Yehouenou Tessi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.