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Case Report
Transverse myelitis after immunization against SARS-CoV-2: A case report
1 Medical student at Iguaçu University - UNIG/RJ, Nova Iguaçu - RJ, Brazil
2 Physician, Neurologist, Adjunct Professor of Medicine at Universidade Iguaçu, Iguaçu University - UNIG/Nova Iguaçu, RJ, Brazil
3 Professor of Neurology - Universidade Iguaçu - UNIG-RJ, Nova Iguaçu - RJ; Physician of the Neurology Service of Nova Iguaçu General Hospital, Nova Iguaçu, RJ, Brazil
4 Department of Neurology of Hospital Geral de Nova Iguaçu, Adjunct Professor of Medicine at Iguaçu University - UNIG/Nova Iguaçu, RJ, Brazil
Address correspondence to:
Antônio Marcos da Silva Catharino
Rua Gavião Peixoto 70, Room 811, CEP 24.2230-100, Icaraí, Niterói-RJ,
Brazil
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Article ID: 101404Z01DP2023
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How to cite this article
Pereira DA, Leme LE, Dantas SAB, Neves MAO, Canedo GM Jr, da Silva Catharino AM. Transverse myelitis after immunization against SARS-CoV-2: A case report. Int J Case Rep Images 2023;14(2):21–25.ABSTRACT
Introduction: Transverse myelitis (TM) is a clinical syndrome of varied etiology, one of its causes being the immune-mediated lesion caused by the COVID-19 vaccine. It causes sensory, motor, and autonomic dysfunctions that can be bilateral, unilateral, or asymmetrical and that can change rapidly. The clinical presentation of TM is mainly represented by bilateral weakening of the lower limbs (LL), but it varies depending on the level of the spinal cord involved. Early diagnosis and treatment can benefit recovery and prevent a recurrence.
Case Report: We report the case of a 50-year-old man, an engineer by profession, who reported that in the second dose of immunization against SARS-CoV-2, he began to have a tingling sensation (dysesthesia) in the lower limbs. After four months, between the second and third doses, about five months, a new clinical picture of paresis had erupted, associated with tactile, thermal, and painful hypoesthesia.
Conclusion: Due to the significant impact of COVID-19 on health, especially about neurological impacts, disorders associated with the vaccine should always be considered when approaching patients after vaccination. Post-vaccination TM, as it has a difficult diagnosis (excluding other causes) and a variable prognosis (from total recovery without damage to complete paraplegia, respiratory failure, or upper cervical injury), establishing its diagnosis in an early diagnosis is essential for a better prognosis.
Keywords: COVID-19, Transverse myelitis, Vaccine
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Acknowledgments
The authors acknowledge the individuals here who contributed to the work but do not qualify for authorship.
Author ContributionsDaniel Antunes Pereira - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Luiza Eyer Leme - Substantial contributions to conception and design, Interpretation of data, Drafting the article, Final approval of the version to be published
Shara Aline Bueno Dantas - Substantial contributions to conception and design, Interpretation of data, Drafting the article, Final approval of the version to be published
Marco Antônio Orsini Neves - Substantial contributions to conception and design, Acquisition of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Gilberto Canedo M Jr - Substantial contributions to conception and design, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Antônio Marcos da Silva Catharino - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Daniel Antunes Pereira et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
