Case Report


Paraneoplastic IgA nephropathy and IgA vasculitis in mesothelioma

,  ,  ,  ,  

1 Internal Medicine Resident, Department of Medicine, Penn State Milton S. Hershey Medical Centre, 500 University Drive, Hershey, Pennsylvania, USA

2 Nephrology Fellow, Department of Medicine (Nephrology), Penn State Milton S. Hershey Medical Centre, 500 University Drive, Hershey, Pennsylvania, USA

3 Department of Pathology, Penn State Milton S. Hershey Medical Centre, 500 University Drive, Hershey, Pennsylvania, USA

4 Assistant Professor of Medicine, Department of Medicine (Nephrology), Penn State Milton S. Hershey Medical Centre, 500 University Drive, Hershey, Pennsylvania, USA

Address correspondence to:

Gurwant Kaur

MD, FASN, Assistant Professor of Medicine, Department of Medicine (Nephrology), Penn State Milton S. Hershey Medical Centre, 500 University Drive, Hershey, Pennsylvania 17033,

USA

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Article ID: 101063Z01KB2019

doi: 10.5348/101063Z01KB2019CR

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How to cite this article

Bartolomeo K, Al Zein S, Cullen J, Abendroth C, Kaur G. Paraneoplastic IgA nephropathy and IgA vasculitis in mesothelioma. Int J Case Rep Images 2019;10:101063Z01KB2019.

ABSTRACT


Immunoglobulin A (IgA) vasculitis and IgA nephropathy have been associated with underlying malignancies when present in adult populations. To date, we have found only two previously reported cases of IgA vasculitis and one IgA nephropathy case associated with mesothelioma, with our patient being the fourth. Our case describes a patient with biopsy proven IgA nephropathy and IgA vasculitis with known malignant mesothelioma who presented with features of lower extremity purpura, leukocytoclastic rash, and dialysis-dependent acute kidney injury (AKI).

Keywords: Acute kidney injury, Crescentic IgA nephropathy, Henoch–Schönlein purpura, IgA nephropathy, IgA vasculitis, Mesothelioma

SUPPORTING INFORMATION


Author Contributions

Korey Bartolomeo - Drafting the article, Final approval of the version to be published

Said Al Zein - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published

Joan Cullen - Acquisition of data, Drafting the article, Final approval of the version to be published

Catherine Abendroth - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Gurwant Kaur - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Guarantor of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2019 Korey Bartolomeo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.