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Case Report
Synchronous carcinomas of primary origin: Squamous cell carcinoma of the skin and clear cell renal cell carcinoma
1 Medical Doctor , Bogota, Colombia
2 Jhon medical Student, Chia, Cundinamarca, Colombia
3 Medical doctor, Chia , Cundinamarca, Colombia
Address correspondence to:
Carolina Cortes
Medical doctor, Bogota,
Colombia
Message to Corresponding Author
Article ID: 101013Z01CC2019
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Cortes C, Bermúdez J, Toscano A, Pérez H. Synchronous carcinomas of primary origin: Squamous cell carcinoma of the skin and clear cell renal cell carcinoma. Int J Case Rep Images 2019;10:101013Z01CC2019.ABSTRACT
Introduction: Synchronous carcinomas are defined multiple primary neoplasms occurring in different locations belonging to different morphologic or histologic origin ocurrin at the same time in a patient. This is the first report of a cutaneous squamous cell carcinoma presenting synchronically with a clear renal cell carcinoma, confirming is not a metastatic process.
Case Report: A 53-year-old man had a clinical course of eight months of evolution, of a continuously growing mass in the left gluteus and thigh with inguinal adenopathies, in the same place of a previously burn area, for which complementary imaging studies were indicated to establish the extent of the lesion, with an incidental finding of a tumor in left kidney. Biopsies of the gluteal and left kidney lesions were performed, showing a verrucous variant squamous cell carcinoma in gluteal region and a clear cell differentiation concordant with clear cell renal cell carcinoma in left kidney.
Conclusion: Synchronous carcinoma implies a complex interactions between genetic and environmental factors for its development. Clinical manifestations usually presents in advance stages of both carcinomas, but can be detected with extension studies as in this case.
Keywords: Carcinoma, Kidney, Multiple, Skin, Synchronous
SUPPORTING INFORMATION
Author Contributions
Carolina Cortes - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jhon Bermúdez - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Andrés Toscano - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Héctor Pérez - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this case report.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Open Access StatementAll relevant data are within the paper and its Supporting Information files.
Copyright© 2019 Carolina Cortes et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
