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Case Report
Hepatocellular Carcinoma in Situs Inversus Totalis: A case report and literature review
1 Department of Surgery, University of Pennsylvania,3400 Spruce Street, Philadelphia
2 Department of Surgery, Mount Sinai Medical Center, Miami Beach, Florida
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Kai Zhao
MD, Department of Surgery, University of Pennsylvania, 3400 Spruce Street,
Philadelphia
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Article ID: 100999Z01KZ2019
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Zhao K, Bao P. Hepatocellular Carcinoma in Situs Inversus Totalis: A case report and literature review. Int J Case Rep Images 2019;10:100999Z01KZ2019.ABSTRACT
Introduction: Situs inversus Totalis (SIT) is a rare congenital condition that occurs in less than 1% of the population. Hepatocellular carcinoma of fibrolamellar type is a rare variant of hepatocellular carcinoma comprising less than 1% of all liver cancer.
Case Report: We report a case of Hepatocellular Carcinoma (HCC) of fibrolamellar type with Situs Inversus Totalis (SIT) that was treated by hepatectomy. A 49-year old female with diagnosis of SIT was found to have a heterogeneous mass on her “left” lobe of her liver (medial aspect). Tumor feature on MRI was consistent with HCC of the Fibrolamellar type. She underwent an ultimately successful “left” hepatectomy with resection of segment II, III, IV and partially I. Final pathology confirmed fibrolamellar HCC.
Conclusion: FLHCC and SIT are both exceedingly rare. Surgical resection of FLHCC in our patient with SIT was technically challenging.
Keywords: Fibrolamellar, Hepatocellular carcinoma, Situs inversus totalis
SUPPORTING INFORMATION
Author Contributions
Kai Zhao - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Philip Bao - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this case report.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Kai Zhao et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
