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Case Series
Rare secondary lymphomas involving the brain
1 Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 2200 Northern Blvd, Suite 104, Greenvale, NY, USA
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Pallavi Khattar
MD, Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 2200 Northern Blvd, Suite 104, Greenvale, NY 11548,
USA
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Article ID: 100082Z11ZZ2024
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How to cite this article
Hossein-Zadeh Z, Geetha S, Seth N, Edappallath S, Bedi P, Zhang X, Li JY, Khattar P. Rare secondary lymphomas involving the brain. J Case Rep Images Pathol 2024;10(2):27–31.ABSTRACT
Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Accordingly, the clinical features and outcomes are not well described. Anaplastic large cell lymphoma (ALCL) is a rare and aggressive type of non-Hodgkin lymphoma that can arise in various parts of the body, including the central nervous system (CNS). Secondary ALCL involving the CNS is more common than primary disease. In general, these rare lymphomas in the CNS present with a predilection for parenchymal lesions with dural extension. Here we report two cases with metastatic/secondary lymphomas involving the CNS, with review of the literature. We believe awareness of these rare entities involving the CNS is beneficial for pathologists and neuropathologists.
Keywords: Anaplastic large cell lymphoma, CNS lymphoma, Hodgkin lymphoma, Metastatic brain lymphoma, Primary versus metastatic CNS lymphomas
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Author Contributions
Zarrin Hossein-Zadeh - Acquisition of data, Drafting the article, Final approval of the version to be published
Saroja Geetha - Acquisition of data, Drafting the article, Final approval of the version to be published
Neha Seth - Acquisition of data, Drafting the article, Final approval of the version to be published
Sushmitha Edappallath - Acquisition of data, Drafting the article, Final approval of the version to be published
Puneet Bedi - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Xinmin Zhang - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Jian Yi Li - Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Pallavi Khattar - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Zarrin Hossein-Zadeh et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
