Case Report
 
Iron deficiency anemia in monoclonal gammopathy of undetermined significance
Kenji Shinohara
Department of Medicine, Towa Municipal Hospital, Yamaguchi, Japan

Article ID: 100900Z01KS2018
doi: 10.5348/100900Z01KS2018CR

Corresponding Author:
Kenji Shinohara,
Towa Municipal Hospital,
Yamaguchi, Japan

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How to cite this article
Shinohara K. Iron deficiency anemia in monoclonal gammopathy of undetermined significance. Int J Case Rep Images 2018;9:100900Z01KS2018.


ABSTRACT

Introduction: Anemia in plasma cell in multiple myeloma (MM) is found in 60–90 % of the patients, and is usually noromocytic and normochromic. Rarely, iron deficiency anemia (IDA) occurs with microcytic and hypochromic red blood cells, however the pathogenesis remains unknown.

Case Report: A 75-year-old male with monoclonal gammopathy of undetermined significance (MGUS) had iron deficiency anemia (IDA) with microcytic and hypochromic red blood cells. The serum levels of erythropoietin (EPO), interleukin-6(IL-6) and hepcidin-25 were normal. The administration of oral iron ameliorated IDA.

Conclusion: The cause of IDA in the present patient was unknown. The administration of oral iron improved IDA.

Keywords: Hepcidin, Iron deficiency anemia, Monoclonal gammopathy


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Acknowledgements
The author thanks Dr. Toru Takahashi, Department of Hematology, Yamaguchi Grand Medical Center, for taking the microscopic picture of bone marrow aspirate smear.
Author Contributions
Kenji Shinohara – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of Submission
The corresponding author is the guarantor of submission.
Source of Support
None
Consent Statement
Written informed consent was obtained from the patient for publication of this case report.
Conflict of Interest
Author declares no conflict of interest.
Copyright
© 2018 Kenji Shinohara et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.