Case Report
 
Granulocytic sarcoma of epidural mass with acute myeloid leukemia
Garima Singh1, Ashutosh Kumar2, Mili Jain3, Rashmi Kushawa4, Arun A. Kumar5, Durg Pratap Singh6
1MD, Assistant Professor, Department of pathology, G.C.R.G Institute of Medical Science & Hospital, Lucknow, Uttar Pradesh, India
2MD, Head of pathology department, Department of pathology, King George Medical College Lucknow, Uttar Pradesh, India
3MD, Assistant Professor, Department of pathology, King George Medical College Lucknow, Uttar Pradesh, India
4MD, Associate Professor, Department of pathology, King George Medical College Lucknow, Uttar Pradesh, India
5MD, Fellowship, Department of pathology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India
6MBBS, Medical Officer, Primary Health System, Rajghat Narora Bulandshahar, Uttar Pradesh, India

Article ID: Z01201704CR10784GS
doi:10.5348/ijcri-201745-CR-10784

Address correspondence to:
Garima Singh
Complete Mailing Address: B-256 Kanhaiya Nagar
Lucknow, Uttar Pradesh,


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How to cite this article
Singh G, Kumar A, Jain M, Kushawa R, Kumar AA, Singh DP. Granulocytic sarcoma of epidural mass with acute myeloid leukemia. Int J Case Rep Images 2017;8(4):261–264.


Abstract

Extramedullary manifestations of acute leukemia include a wide variety of clinically presentation that often pose difficulty in diagnosis and treatment of myeloid sarcoma. We present a case of a five-year-old boy with initial complaints of radicular pain of both lower limbs and urinary retention. On MRI, compression by epidural mass was identified, which was shown to be an extramedullary myeloid sarcoma diagnosed on the basis of Auer rods containing blasts in peripheral blood smear and bone marrow. Diagnosis was confirmed with flow cytometry and induction chemotherapy was started. Initial neurological presentation of paraplegia due to chloroma is extremely rare in myeloid leukemia with very few case reports published earlier.

Keywords: Extramedullary, Flow cytometry, Myeloid, Sarcoma



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Author Contributions
Garima Singh – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ashutosh Kumar – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Mili Jain – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Final approval of the version to be published
Rashmi Kushawa – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Final approval of the version to be published
Arun A. Kumar – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Final approval of the version to be published
Durg Pratap Singh – Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Garima Singh et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.