Case Report
 
Diabetes insipidus secondary to gastrointestinal stromal tumor
Muhammad Imran Butt1, Muhammad Asif Shahzad2
1MBBS, Medical Registrar, department of medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia.
2MBBS, Advance trainee, department of medicine, Lyell McEwin Hospital, Adelaide, SA, Australia.

Article ID: Z01201611CR10720MB
doi:10.5348/ijcri-2016132-CR-10720

Address correspondence to:
Muhammad Imran Butt
Department of Medicine, Sir Charles Gairdner Hospital
Hospital Avenue, Nedlands
Perth, WA
Australia, 6009

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How to cite this article
Butt MI, Shahzad MA. Diabetes insipidus secondary to gastrointestinal stromal tumor. Int J Case Rep Images 2016;7(11):754–757.


Abstract
Introduction: Gastrointestinal stromal tumors (GISTs) are considered the most common mesenchymal tumors of the gastrointestinal tract, representing 1% of gastrointestinal malignancies. But to our knowledge has never been reported to be associated with diabetes insipidus (central or nephrogenic).
Case Report: A 68-year-old female was admitted to hospital for investigation of delirium associated with polydipsia and polyuria. She developed hematemesis in hospital which required further investigations. Patient was found to have GIST, diagnosed histologically, associated with diabetes insipidus. She required ICU admission and developed nosocomial pneumonia. Despite appropriate treatment, our patient died.
Conclusion: Gastrointestinal stromal tumors usually present as subepithelial neoplasms of gastrointestinal tract (GIT). However, there has been no association described so far between GISTs and diabetes insipidus and needs further work up to evaluate the link between the two entities.

Keywords: Diabetes insipidus, Gastrointestinal, Stromal, Tumor


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Author Contributions
Muhammad Imran Butt – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Muhammad Asif Shahzad – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Muhammad Imran Butt et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.