Case Report
 
Synchronous carcinoma breast with renal cell carcinoma: A case report
Tej Prakash Soni1, Sajal Goel2, Lalit Mohan Sharma3, Anil Kumar Gupta4, Shantanu Sharma5, Ravindra Gothwal6
1MD, Consultant, Dept. of Radiation Oncology, Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Rajasthan, India.
2DNB, Senior Resident, Dept. of Radiation Oncology, Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Rajasthan, India.
3MD, (Sr. Consultant, Dept. of Medical Oncology, Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Rajasthan, India.
4MS, Sr. Consultant, Dept. of Surgical Oncology, Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Rajasthan, India.
5MD, Associate Professor, Dept. of Radiotherapy, S.M.S. Medical College & Hospital, Jaipur, Rajasthan, India.
6MD, Associate Professor, Dept. of Radiotherapy, S.M.S. Medical College & Hospital, Jaipur, Rajasthan, India.

Article ID: Z01201611CR10713TS
doi:10.5348/ijcri-2016125-CR-10713

Address correspondence to:
Tej Prakash Soni
Dr. Tej Prakash Soni, Consultant, Dept. of Radiation Oncology
Bhagwan Mahaveer Cancer Hospital & Research Centre
JLN Road, Jaipur, Rajasthan
India, Pincode 302017

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How to cite this article
Soni TP, Goel S, Sharma LM, Gupta AK, Sharma S, Gothwal R. Synchronous carcinoma breast with renal cell carcinoma: A case report. Int J Case Rep Images 2016;7(11):720–723.


Abstract
Introduction: Incidence of double malignancy (synchronous or metachronous) has increased significantly. Renal cell cancer or Breast Cancer as second primaries are reported in the literature, but synchronous carcinoma breast with renal cell carcinoma is extremely rare. We are reporting a case of carcinoma breast with synchronous renal cell carcinoma.
Case Report: A 38-year-old female was investigated for a lump in right breast. Biopsy from breast lump was reported as infiltrating duct carcinoma. Metastatic workup revealed a large mass at lower pole of right kidney. Right MRM and right radical nephrectomy were done for synchronous carcinoma breast and renal cell carcinoma.
Conclusion: Genetic predisposition, tobacco, HPV, improvement in survival and long term surveillance after first primary cancer treatment, history of radiation or chemotherapy can be associated with second cancer but exact cause of second cancer is still unknown. Larger studies and research is warranted as the risk of double malignancy has been increased substantially. The plausible mechanisms behind the synchronous cancers have to be investigated.

Keywords: Carcinoma breast, Rare, Renal cell carcinoma, Synchronous


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Author Contributions
Soni Tej Prakash – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Goel Sajal – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sharma Lalit Mohan – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Gupta Anil Kumar – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sharma Shantanu – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Gothwal Ravindra – Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Soni Tej Prakash et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.