 |
|
 |
|
Case Report
| ||||||
| Seronegative lupus membranous nephropathy | ||||||
| Mandya Chikkalingaiah Kiran | ||||||
|
Nephrologist, Eastern Kentucky Nephrology Consultants, Prestonsburg, KY USA.
| ||||||
| ||||||
|
[HTML Full Text]
[PDF Full Text]
[Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar] 
|
| How to cite this article |
| Chikkalingaiah KBM. Seronegative lupus membranous nephropathy. Int J Case Rep Images 2016;7(10):624–627. |
|
Abstract
|
|
Introduction:
Lupus nephritis represents the greater part of systemic lupus erythematosus (SLE) involvement. Antinuclear antibody (ANA) is positive in more than 95% of SLE population. Literature depicts the prevalence of ANA negativity around 1–5% and more prevalent in young females as seropositive lupus. Existence of full-house nephropathy is generally associated with lupus nephritis.
Case Report: We present a case of full-house nephropathy in a 24-year-old female patient with negative serology for SLE presenting with nephrotic syndrome. Renal biopsy revealed tubuloreticular inclusions (TRIs) in endothelial cells differentiating itself from rarer C1q nephropathy. Patient had partial response with conventional immunotherapy with mycophenolate mofetil (MMF) and prednisone. Conclusion: The role of B cell depleting therapy in seronegative lupus; this population needs to be explored in future. | |
|
Keywords:
Full house nephropathy, Lupus nephritis, Seronegative lupus, Tubuloreticular inclusions
| |
|
[HTML Full Text]
[PDF Full Text]
|
|
Author Contributions
Mandya Chikkalingaiah Kiran – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
|
Guarantor of submission
The corresponding author is the guarantor of submission. |
|
Source of support
None |
|
Conflict of interest
Authors declare no conflict of interest. |
|
Copyright
© 2016 Mandya Chikkalingaiah Kiran et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
|
|