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| Dengue and typhoid co-infection: A case report from a tertiary care hospital in South India | ||||||
| Vigna Seshan R.V.1, Gopalsamy S.2, Padma Srikanth3 | ||||||
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1PhD scholar, Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Porur, Chennai-600116.
2Tutor, Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Porur, Chennai-600116. 3Professor, Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Porur, Chennai-600116. | ||||||
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| How to cite this article |
| Vigna SRV, Gopalsamy S, Srikanth P. Dengue and typhoid co-infection: A case report from a tertiary care hospital in South India. Int J Case Rep Images 2016;7(10):563–565. |
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Abstract
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Introduction:
Acute undifferentiated febrile illness is the most common presenting symptom in both adults and children during the monsoon. Incidence of both vector- and water-borne diseases are highest during these seasons, co-infections of dengue with typhoid, malaria, leptospirosis, scrub typhus and other arboviruses can occur in endemic areas. Co-infections of dengue with typhoid have been reported sparsely and are known to present with overlapping symptoms making the clinical diagnosis difficult.
Case Series: We report two confirmed cases of dengue and typhoid co-infection during the monsoon of 2013 from a tertiary care centre in Chennai. Both the patients presented with high grade fever with headache, myalgia and gastrointestinal symptoms. They were admitted to inpatient units with provisional diagnosis of dengue disease, both the patients were confirmed with the diagnosis of dengue, one patient was positive for dengue virus by Real time PCR and other was positive for dengue specific IgM. In view of the persistent fever and associated gastrointestinal symptoms various diagnostic test were performed, which showed that there was a co-infection with typhoid fever. Both the patients were treated with appropriate antibacterial agents and discharged after complete recovery. Conclusion: Dual infections are difficult to diagnose especially in endemic areas during the rainy season as patients present with undifferentiated fever. Co-infections have to be suspected in cases with atypical disease presentations or prolonged fever. | |
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Keywords:
Acute febrile illness, Co-infection, Dengue virus, Typhoid
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Author Contributions:
Vigna Seshan R.V. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Gopalsamy S. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Padma Srikanth – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2016 Vigna Seshan R.V. et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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