Case Report
 
Crohn's disease successfully treated with the paleolithic ketogenic diet
Csaba Tóth1, Andrea Dabóczi1, Mark Howard2, Nicholas J. Miller2, Zsófia Clemens1,3
1Paleomedicina Hungary Ltd., Evolutionary Medicine Working Group, Budapest, Hungary.
2Biolab Medical Unit, London, United Kingdom.
3Neurological Department, University of Pécs, Pécs, Hungary.

Article ID: Z01201609CR10690CT
doi:10.5348/ijcri-2016102-CR-10690

Address correspondence to:
Zsófia Clemens
PhD, Paleomedicina Hungary Ltd., Evolutionary Medicine Working Group
Hidász u. 3. H-1026, Budapest, Hungary
Department of Neurology, University of Pécs, Rét u. 2, H-7623, Pécs
Hungary

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How to cite this article
Tóth C, Dabóczi A, Howard M, Miller NJ, Clemens Z. Crohn's disease successfully treated with the paleolithic ketogenic diet. Int J Case Rep Images 2016;7(10):570–578.


Abstract
Introduction: Crohn's disease is regarded as having no curative treatment. Previous reports on dietary therapy of Crohn's disease indicate no major success.
Case Report: Here we report a severe case of Crohn's disease where we successfully applied the paleolithic ketogenic diet. Dietary therapy resulted in resolution of symptoms, normalized laboratory parameters as well as gradual normalization of bowel inflammation as evidenced by imaging data and normalization of intestinal permeability as shown by the polyethylene glycol (PEG 400) challenge test. The patient was able to discontinue medication within two weeks. Currently, he is on the diet for 15 months and is free of symptoms as well as side effects.
Conclusion: We conclude that the paleolithic ketogenic diet was feasible, effective and safe in the present case.

Keywords: Crohn's disease, Dietary therapy, Inflammatory bowel disease, Ketogenic diet, Paleolithic diet


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Author Contributions
Csaba Tóth – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Andrea Dabóczi – Acquisition of data, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mark Howard – Acquisition of data, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Nicholas J. Miller – Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Zsófia Clemens – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Csaba Tóth et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.