Case Series
 
Not safe for consumption: Synthetic cannabinoids causing fatal acute rhabdomyolysis in two young men
Anthea B. Mahesan Paul1, Lary Simms1, Abraham Ebenezer Paul1, Christopher Schmidseder1, Andrew A. Mahesan2, Jojo Yorke2
1Clark County Coroners Office, 1704 Pinto Lane, Las Vegas, Nevada, USA, 89106.
2Ross University, School of Medicine, Dominica.

Article ID: Z01201607CR10073AP
doi:10.5348/ijcri-201612-CS-10073

Address correspondence to:
Anthea B. Mahesan Paul
C/O Dr. Lary Simms, D.O., M.P.H, Medical Examiner
Clark County Coroners Office
1704 Pinto Lane, Las Vegas, Nevada
USA, 89106

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How to cite this article
Paul ABM, Simms L, Paul AE, Schmidseder C, Mahesan AA, Yorke J. Not safe for consumption: Synthetic cannabinoids causing fatal acute rhabdomyolysis in two young men. Int J Case Rep Images 2016;7(7):431–435.


Abstract
Introduction: Synthetic cannabinoids are a class of recreational drugs that are included in the growing epidemic of synthetic recreational drugs sweeping the United States. Synthetic cannabinoids look, feel and act like Marijuana with dangerous and potentially fatal adverse effects. Synthetic cannabinoids, in addition are not detected by routine urine toxicology screening, and thus the magnitude of its prevalence is unknown.
Case Series: In this case series, we report two cases of fatal acute rhabdomyolysis associated with synthetic cannabinoid use in previously healthy young men. The strong correlation found by detailed history, clinical evaluation, and laboratory tests including the negative universal drug screen strongly suggests an association between synthetic cannabinoid use and fatal acute rhabdomyolysis in both cases.
Conclusion: Synthetic recreational drug use, including synthetic cannabinoids should be included in the differential diagnosis for acute rhabdomyolysis in young people with negative universal drug screens and initiatives should be taken to educate physicians and the general public of the serious consequences of synthetic cannabinoid use.

Keywords: Synthetic cannabinoids, Spice, Rhabdomyolysis


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Author Contributions:
Anthea B. Mahesan Paul – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Lary Simms – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Abraham Ebenezer Paul – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Christopher Schmidseder – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Andrew A. Mahesan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jojo Yorke – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
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Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Anthea B. Mahesan Paul et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.