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Case Series
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| Wernicke's syndrome associated with hyperemesis gravidarum | ||||||
| Mohamed Amine Bouslama1, Afraa Brahim1, Ahmed Nedhir Sfeyhi2, Khalil Tarmiz3, Khaled Ben Jazia3 | ||||||
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1MD-PhD, Anesthesia and Intensive care Department, University Hospital FarhatHached, Institute, Sousse, Tunisia.
2MD, Anesthesia and Intensive Care Department, University Hospital FarhatHached, Institute, Sousse, Tunisia. 3PhD-professor, Anesthesia and Intensive Care Department, University Hospital FarhatHached, Institute, Sousse, Tunisia. | ||||||
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| How to cite this article |
| Bouslama MA, Brahim A, Sfeyhi AN, Tarmiz K, Jazia KB. Wernicke's syndrome associated with hyperemesis gravidarum. Int J Case Rep Images 2016;7(7):427–430. |
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Abstract
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Introduction:
Hyperemesis gravidarum during pregnancy can be complicated by Wernicke's encephalopathy (WE). It is a neuropsychiatric syndrome due to thiamine deficiency generated by increased requirement and loss. It is a fatal but preventable complication. The management and prevention of this disorder is still unclear for lack of guidelines.
Case Series: These are two cases of Wernicke's encephalopathy complicating hyperemesis gravidarum occurred in two women during the first trimester of pregnancy. Diagnosis was confirmed by MRI scan, and the treatment consisted of intravenous thiamine and parenteral nutrition with a good maternal and fetal outcome. Conclusion: Wernicke's encephalopathy must be suspected in women showing its characteristic clinical signs to avoid worse outcome, such maternofetal death or permanent neuromuscular sequelae. Medical management by thiamine is simple and efficient. | |
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Keywords:
Esophageal rupture, Hyperemesis gravidarum, Thiamine deficiency, Wernicke's encephalopathy
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Author Contributions:
Mohamed Amine Bouslama – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Afraa Brahim – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Ahmed Nedhir Sfeyhi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Khalil Tarmiz – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Khaled Ben Jazia – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2016 Mohamed Amine Bouslama et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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About The Authors
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