Case Report
 
Medullary thyroid carcinoma associated with multiple myeloma: A case report
Seyyed Mohammadreza Mortazavizadeh1, Yasaman Ayoughi2, Fariba Binesh3, Moein Karbalaeian4
1Hematologist/oncologist, Assistant Professor of Internal Department of Medical School of Islamic Azad University of Yazd.
2Student of Medicine, Division of General Medicine of Medical School of Islamic Azad University of Yazd.
3Pathologist, Associated Professor of Clinical Pathology Department of Shaheed Sadoughi Medical School of Yazd University.
4Student of Medicine, Division of General Medicine of Medical School of Shaheed Sadoughi Medical School of Yazd University.

Article ID: Z01201607CR10669SM
doi:10.5348/ijcri-201681-CR-10669

Address correspondence to:
Seyyed Mohammadreza Mortazavizadeh
Hematologist/oncologist, Assistant Professor of Internal Department of Medical School of Islamic Azad University of Yazd

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How to cite this article
Mortazavizadeh SM, Ayoughi Y, Binesh F, Karbalaeian M. Medullary thyroid carcinoma associated with multiple myeloma: A case report. Int J Case Rep Images 2016;7(7):458–462.


Abstract
Introduction: The co-existence multiple myeloma (MM) and another cancer have been reported severally in literature, but medullary thyroid carcinoma (MTC) as a second cancer with multiple myeloma is an extremely rare case, to our knowledge, there are no prior reports of these concurrent cancers.
Case Report: A 54-year-old man was admitted with chief complain of bone pain, clinical investigation revealed, lytic bone lesions and infiltration of plasma cells in bone marrow and patient with diagnosis of multiple myeloma received chemotherapy, he was in partial remission, but nine months later a solitary nodule was founded in his thyroid, with high levels of calcitonin and fine needle aspiration (FNA) reported the medullary thyroid carcinoma, after total thyroidectomy which confirmed this cancer the patient recovered and now he is followed- up for these cancers.
Conclusion: Diagnosis of secondary cancer is important because: first to distinguish secondary malignancy from metastatic cancer and then try to investigate the etiology of this association.

Keywords: Medullary thyroid cancer, Multiple Myeloma, Secondary malignancy, Thyroid carcinoma


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Author Contributions
Seyyed Mohammad Reza Mortazavizadeh – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Yasaman Ayoughi – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Fariba Binesh – Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Moein Karbalaeian – Acquisition of data, or analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
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The corresponding author is the guarantor of submission.
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Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Seyyed Mohammad Reza Mortazavizadeh et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.