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Case Report
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| Successful treatment of Hepatitis C virus infection in a renal transplant patient with ribavirin and sofosbuvir: A case report | ||||||
| Nawfal R. Hussein1, Zana Sidiq Mohammed Saleem2 | ||||||
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1MD, Department of Internal Medicine, College of Medicne, Univversity of Duhok, Duhok, Iraq.
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| Hussein NR, Saleem ZSM. Successful treatment of Hepatitis C virus infection in a renal transplant patient with ribavirin and sofosbuvir: A case report. Int J Case Rep Imag 2016;7(6):370–373. |
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Abstract
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Introduction:
In transplant patients, chronic hepatitis C virus could not be treated with classical interferon containing regimen as it is associated with serious complications including graft rejection. Though directly acting antivirals (DAAs) are potent for the treatment of HCV, such drugs are not been approved for the treatment of HCV in organ transplant subjects.
Case Report: We described a 29-year-old female patient with hepatitis C virus genotype 4 infection who was treatment naïve. The patient was diagnosed with HCV and HBV years after renal transplant operation. Treatment with sofosbuvir and ribavirin allowed for rapid decrease of serum HCV RNA. The patient developed anemia in two different occasions during the treatment period and received blood transfusion. Sustained virologic response was achieved. Conclusion: The use of directly acting antivirals may allow a safe way to treat patients with renal transplant and chronic HCV. Such a treatment may improve the outcome of renal transplant in those patients with chronic HCV. | |
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Keywords:
Iraq, Ribavirin, Renal transplant, Sofosbuvir
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Author Contributions
Nawfal R. Hussein – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Zana Sidiq Mohammed Saleem – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2016 Nawfal R. Hussein et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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