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Case Report
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| Extranodal T- NK-cell lymphoma, nasal type masquerading as ileal inflammatory bowel disease | ||||||
| Olanma Y. Okoji1, Abul Ala Syed Rifat Mannan2, Peter R. Holt3, Donald P. Kotler4 | ||||||
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1MD, Clinical Fellow. Department of Medicine, Gastroenterology. Mount Sinai St ' Roosevelt Hospital. 1111 Amsterdam Ave, New York City, New York, United States of America.
2MD, Pathology Resident. Department of Pathology. Mount Sinai St ' Roosevelt Hospital. 1111 Amsterdam Ave, New York City, New York, United States of America. 3MD,Senior Research Associate - Laboratory of Biochemical Genetics and Metabolism. The Rockefeller University. 1230 York Avenue. New York City, New York, United States of America. 4MD, Chief, Division of Gastroenterology and Liver Disease. Mount Sinai St ' Roosevelt Hospital. 1111 Amsterdam Ave, New York City, New York, United States of America. | ||||||
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| How to cite this article |
| Okoji OY, Mannan AASR, Holt PR, Kotler DP. Extranodal T- NK-cell lymphoma, nasal type masquerading as ileal inflammatory bowel disease. Int J Case Rep Images 2015;6(12):738–742. |
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Abstract
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Introduction:
ENKL (Extranodal Natural killer/T cell lymphoma) of the gastrointestinal tract can be indistinguishable from Inflammatory bowel disease or from an infectious etiology affecting the terminal ileum.
Case Report: We report a case of a 36-year-old Mexican male who presented with severe non-specific lower abdominal pain, fever and laboratory data suggestive of a systemic disease. The initial differential diagnosis was inflammatory bowel disease because of the non-specific finding of terminal ileum thickening seen on a computed tomography scan. As occurs in most patients with ENKL, the patient died rapidly in the setting of an aggressive lymphoma and the complication of intestinal perforation. Conclusion: The differential diagnosis of localized inflammation of the distal ileum most commonly is seen in Crohn's disease but the differential diagnosis is very broad and includes aggressive lymphomas such as ENKL. This diagnosis should be considered in a clinical setting of a patient from Asia or Latin America with the appearance of unexplained small bowel localized inflammatory disease. Early recognition and treatment can be life-saving. | |
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Keywords:
Abdominal pain, Gastrointestinal lymphoma, Ileitis, Inflammatory bowel disease
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Author Contributions
Olanma Y. Okoji – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Abul Ala Syed Rifat Mannan – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Peter R. Holt – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Donald P. Kotler – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Olanma Y. Okoji et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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