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Case Report
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| A case of hardening of the skin and scleroderma like changes on biopsy: Is it scleroderma or not? A review of pseudoscleroderma and differential diagnosis | ||||||
| Travis C. Sizemore1, Gulzar Merchant1, Katharine Whitfield1 | ||||||
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1Internal Medicine Department, University of South Carolina Greenville Health System.
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| How to cite this article |
| Sizemore TC. A case of hardening of the skin and scleroderma like changes on biopsy: Is it scleroderma or not? A review of pseudoscleroderma and differential diagnosis. Int J Case Rep Images 2015;6(9):546–551. |
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Abstract
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Scleroderma is an autoimmune connective tissue disease characterized by pervasive systemic multiple organ fibrosis. Definitive diagnosis can be difficult as this disease has a highly variable disease spectrum and course. Further complicating matters, there exist several less commonly known imitators, termed pseudosclerodermas, which force a more open differential than might be presumed initially. This case emphasizes the importance of skin biopsy while not on steroids and also the need to maintain a broad differential even in the setting of biopsy results
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Keywords:
Pseudoscleroderma, Scleromyxedema, Scleroderma
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Author Contributions
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Travis C. Sizemore – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Gulzar Merchant – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Katharine Whitfield – Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Travis C. Sizemore et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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