  |
|
 |
|
Case Report
| ||||||
| Multiple Intracranial Inflammatory Pseudotumors | ||||||
| Christopher C. Gillis1, John A.C. Maguire2, Charles S. Haw3 | ||||||
|
1University of Nebraska Medical Center, Division of Neurosurgery, Omaha, NE.
2University of British Columbia Department of Anatomical Pathology, Vancouver, B.C.. 3University of British Columbia Department of Surgery Division of Neurosurgery, Vancouver, B.C. | ||||||
| ||||||
|
[HTML Full Text]
[PDF Full Text]
[Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar] 
|
| How to cite this article |
| Gillis CC, Maguire JAC, Haw CS. Multiple Intracranial Inflammatory Pseudotumors. Int J Case Rep Images 2015;6(8):488–492. |
|
Abstract
|
|
Introduction:
Inflammatory pseudotumor is a rare intracranial lesion. Reports of multiple intracranial inflammatory pseudotumors are very rare.
Case Report: A 68-year-old female presented with left hemiparesis and sensory neglect and was found to have two homogeneously enhancing lesions on computed tomography (CT) scan near the right rolandic area. The larger of the two lesions was resected with the presumed radiographic and intraoperative diagnosis of meningioma. Pathology demonstrated inflammatory pseudotumor. She re-presented eight months postoperatively with both progression of the remaining lesion and a de novo lesion. Biopsy was done which reaffirmed the diagnosis. The patient was tried on high dose steroid, giving radiographic but not clinical improvement. Treatment was intensified to methotrexate which gave both clinical improvement and radiographic improvement. The patient was then treated with methotrexate giving symptomatic improvement. Conclusion: The differential for extra-axial lesions should include inflammatory pseudotumor. The best treatment for this disease process has not been determined. Surgical resection and steroid therapy may help temporize symptoms and provide a diagnosis but in the case of multiple lesions this likely represents a diffuse intracranial process requiring chemotherapy. | |
|
Keywords:
Central nervous system, Chemotherapy, Craniotomy, Inflammatory pseudotumor, Neoplasms
| |
|
[HTML Full Text]
[PDF Full Text]
|
|
Author Contributions
Christopher C. Gillis – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published John A.C. Maguire – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Charles S. Haw – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
|
Guarantor of submission
The corresponding author is the guarantor of submission. |
|
Source of support
None |
|
Conflict of interest
Authors declare no conflict of interest. |
|
Copyright
© 2015 Christopher C. Gillis et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
|
|